Oncologie

ISSN: 1292-3818 (print) Impact Factor: 0.052
ISSN: 1765-2839 (online) Publication Frequency: Quarterly

About the Journal

Oncologie is aimed to the publication of high quality original research articles, review papers, case report, etc. with an active interest in vivo or vitro study of cancer biology. Study relating to the pathology, diagnosis, and advanced treatment of all types of cancers, as well as research from any of the disciplines related to this field of interest. The journal has English and French bilingual publication.
The French Society of Oncology Surgery (SFCO), associoation francophone des soins oncologiques de support (AFSOS) and the French Federation of Medical Oncologists (FFOM) are affiliated with the journal Oncologie.

Indexing and Abstracting

Science Citation Index Expanded (SciSearch); Journal Citation Reports/Science Edition; SCOPUS; EMBASE; Google Scholar; OCLC; PASCAL; SCImago; Summon by ProQuest

Previously published by Lavoisier (https://www.revuesonline.com/portail/), Oncologie starts to be published by Tech Science Press from 2020. It supports Open Access Policy and an Article Processing Charge (APC) of $1000 US dollars applies to all accepted papers (submitted after 1st February 2021).

Current Issue - Vol.22, No.4, 2020 Most Viewed

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EDITORIAL
Specificities of Ophthalmic Tumors: Usefulness of A National Network
Spécificités des Tumeurs de la Sphère Ophtalmique: Utilité d’un Réseau National
Laurence Desjardins^*
Oncologie, Vol.22, No.4, pp. 189-194, 2020, DOI:10.32604/oncologie.2020.012377
Abstract We describe the most frequent malignant intraocular tumors, conjunctival tumors and some lids and orbital tumors. Primary intraocular malignant tumors are retinoblastoma in children and uveal melanoma in adults. For uveal melanoma, the liver is the most frequent site of metastasis and this is why it is justified to prescribe liver ultrasonography every 6 months to these patients. Metastatic tumors can occur in the uvea and more frequently in the posterior part called the choroid. They are more frequent after breast cancer and lung cancer. Conjunctival tumors can be epithelial (benign papillomas and epidermoid carcinomas) or melanocytic (benign naevi and… More
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ARTICLE
Pathological Examination: Features of Ocular Tumors
Examen Anatomopathologique: Particularités des Tumeurs Oculaires
Sophie Gardrat^*, Vincent Cockenpot
Oncologie, Vol.22, No.4, pp. 195-202, 2020, DOI:10.32604/oncologie.2020.013698
Abstract The pathological examination of ocular tumors has specificities in terms of macroscopic management, microscopic analysis, and molecular examinations requiring special attention. We discuss here the difficulties encountered in the reception in the pathological anatomy laboratory of conjunctival samples, enucleation and orbital exenteration pieces, then detail the diagnostic and theranostic, microscopic and molecular characteristics of ocular tumor pathologies. Conjunctival tumors (epithelial, melanocytic and lymphoid), choroidal tumors (including uveal melanoma) and retinoblastoma are treated. Because of their low frequency and their features, these tumors should be the subject of anatomo-clinical discussions.

Résumé:
L’examen anatomopathologique des tumeurs oculaires comporte des spécificités en termes… More
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ARTICLE
Uveal Melanoma Management for Medical Oncologists in 2020
Prise en charge du mélanome uvéal en oncologie médicale en 2020
Sophie Piperno-Neumann^1,*, Pascale Mariani², Vincent Servois³, Gaelle Pierron⁴, Livia LumbrosoRouic⁵, Alexandre Matet^5,6, Manuel Rodrigues¹, Nathalie Cassoux^5,6
Oncologie, Vol.22, No.4, pp. 203-212, 2020, DOI:10.32604/oncologie.2020.014102
Abstract Uveal melanoma is a rare subtype of melanoma, intrinsically different from cutaneous melanoma. Despite optimal therapeutic management allowing local control of the primary ocular tumor, 20 to 50% of patients develop metastases, mainly localized to the liver, with a poor prognosis and a 12-month median survival from the diagnosis of the metastatic disease. There is a lack of effective treatments in the metastatic setting, and dedicated strategies and trials for uveal melanoma patients are needed, based on identification of new targets and specific preclinical findings.

Résumé:
Le mélanome de l’uvée est un cancer rare, en tous points différent du mélanome… More
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REVIEW
Dietary Inclusions and Exclusions: Preparation Against Cancer
Dheeraj Kumar Sharma¹, Ahsas Goyal^2,*, Shashank Chaturvedi^2,*
Oncologie, Vol.22, No.4, pp. 213-224, 2020, DOI:10.32604/oncologie.2020.014926
Abstract Cancer results due to an imbalance between regulation of cell proliferation and apoptosis. As per the latest data released by World Health Organization (WHO), a large part of global population cannot access proper anticancer therapy, and this imposes a burden of approximately US$ 1.16 trillion on global economy. Relevant studies were identified through electronic searches of Pubmed, Medline, Scopus, Google scholar. In this review, we found that there is extensive range of dietary items whose components can influence either cell proliferation rate or cell death rate or both. Exclusion and avoidance of several dietary items/habits are linked with reduced risk… More
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ARTICLE
The Investigation of Genotype-Phenotype Relationship in Multiple Primary Malignant Neoplasia Patients
Neslihan Duzkale^1,*, Emine Demıral²
Oncologie, Vol.22, No.4, pp. 225-234, 2020, DOI:10.32604/oncologie.2020.014120
Abstract Multiple primary malignant neoplasms (MPMN) are rare tumors that have attracted attention with increasing incidence rates in recent years and where cancer susceptibility genes may play a role in their etiology. In this study, it was aimed to determine the genotype-phenotype correlation in patients with MPMN. From January 2018 to January 2020, thirty patients were analyzed for 59 cancer susceptibility genes and diagnosed with MPMN, using a large multigene panel with Next Generation Sequencing technique (NGS) in Turkey. The mean age of first and second cancer diagnosis of cases were calculated as 42.5 and 49.9 (respectively). These primary cancers were… More
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ARTICLE
Analysis on Characteristics and Nursing Points of Surgical and Interventional Treatment for Elderly Cerebral Aneurysm
Haiying You¹, Jing Li², Xiaojie Wang³, Guodong Zhang⁴, Juan Yang^5,*
Oncologie, Vol.22, No.4, pp. 235-244, 2020, DOI:10.32604/oncologie.2020.014123
Abstract Objective. The purpose was to explore the characteristics and nursing points of surgical and interventional treatment for elderly cerebral aneurysm. Methods. 100 elderly patients with cerebral aneurysm treated in our hospital from January 2017 to December 2019 were selected, and divided into craniotomy group (40 patients with neurosurgical clipping) and interventional surgery group (60 patients with endovascular interventional embolization) according to the treatment method to compare the operation time, hospitalization time, hospitalization expenses, degree of brain injury, complications and prognostic scores of the patients in two groups. Meanwhile, the relationship between the factors (age, aneurysm size, location) and prognosis of… More
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ARTICLE
LncRNA-ATB Can Be a Biomarker for Diagnosis and Prognosis Evaluation of Non-Small Cell Lung Cancer
Nan Geng¹, Wenxia Hu¹, Zhikun Liu², Jingwei Su², Wenyu Sun³, Shaonan Xie⁴, Cuimin Ding^1,*
Oncologie, Vol.22, No.4, pp. 245-254, 2020, DOI:10.32604/oncologie.2020.014125
Abstract Objective: This study was set out to inquire into the expression and clinical significance of lncRNA activated by transforming growth factor β (LncRNA-ATB) and in cancer tissues of patients with non-small cell lung cancer (NSCLC). Methods: LncRNA-ATB in cancer tissues and adjacent tissues of 89 NSCLC patients was detected by quantitative real-time polymerase chain reaction (qRT-PCR), and its clinical diagnostic value in NSCLC was determined by receiver operating characteristic (ROC) curves. Based on the median expression of LncRNAATB in NSCLC tissues, 89 patients were allocated into high- and low-expression groups. The 3-year survival rate was calculated using Kaplan-Meier method and… More
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ARTICLE
Analysis of the Effects of Different Surgical Procedures for the Treatment of Thyroid Cancer on the Expression Levels of IL-17, IL-35, and SIL-2R and the Prognostic Factors
Chuanwei Xu¹, Renju Ding², Chuanping Xu^3,*
Oncologie, Vol.22, No.1, pp. 43-51, 2020, DOI:10.32604/oncologie.2020.012445
Abstract To analyze the effects of different surgical procedures for the treatment of thyroid cancer on the expression levels of serum interleukin-17 (IL-17), IL-35, soluble interleukin-2 receptor (SIL-2R), and the prognostic factors. Seventy-eight patients with differentiated thyroid cancer were selected and grouped as control group (CG) (n = 39, underwent subtotal thyroidectomy) and observation group (OG) (n = 39, underwent total thyroidectomy). The serum IL-17, IL-35, and SIL- 2R expression levels; the incidence of complications; and the differentiated thyroid carcinoma (DTC) relapse rate were compared between the two groups. The serum IL-17 and SIL-2R levels were lower in the OG than… More
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REVIEW
A Narrative Review: Classification of Pap Smear Cell Image for Cervical Cancer Diagnosis
Wan Azani Mustafa^1,*, Afiqah Halim¹, Khairul Shakir Ab Rahman²
Oncologie, Vol.22, No.2, pp. 53-63, 2020, DOI:10.32604/oncologie.2020.013660
Abstract Cervical cancer develops as cells transformation in the cervix of a female that connects the uterus to the vagina. This cancer may impact the columnal epithelial cells of the cervix and therefore can be expanded to the lymphatic and circulatory system (metastasize), sometimes the kidneys, liver, prostate, vagina, and rectum. Many of the cervical cancer patients survived by taking early prevention by undergoing a Pap Smear Test. However, the result of the test usually takes a few weeks which is extremely time-consuming especially at the government hospital. The purpose of this research was to study the detection and classification method… More
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ARTICLE
Diagnostic Performance of Serum miR-586 and miR-493 in Patients with Osteosarcoma
Hao Dang^*
Oncologie, Vol.22, No.1, pp. 35-42, 2020, DOI:10.32604/oncologie.2020.012485
Abstract This study aimed to explore the expression and diagnostic performance of miR-586 and miR-493 in patients with osteosarcoma. We enrolled 63 patients with osteosarcoma treated between May 2016 and May 2019 as the experimental group and 55 healthy volunteers who underwent physical examination during the same period as the control group. We detected miR-586 and miR-493 expression in serum, normal bone tissue, and tumor samples. We also evaluated the relationship between clinical indicators and the miR-586 and miR-493 expression levels. The correlation between the serum and osteosarcoma tissue expression of miR-586 and miR-493 was examined by Pearson analysis. Furthermore, the… More
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ARTICLE
Diagnosis of Lung Cancer Based on Plasma Metabolomics Combined with Serum Markers
Dong Zhang^1,#, Lingxia Tong^2,#, Qingjun Wang¹, Yunfeng Cao³, Yu Gao¹, Donghua Yang¹, Tianhao Bao^4,5, Zhitu Zhu^1,*
Oncologie, Vol.22, No.2, pp. 75-82, 2020, DOI:10.32604/oncologie.2020.012376
Abstract Predicting the onset and metastasis of early tumor is the primary means of improving lung cancer prognosis. The purpose of this study was to identify the ability of plasma metabolomics combined with blood markers to establish benign lung disease versus lung cancer regression models. Blood samples were collected from 174 lung cancer patients, 350 benign lung disease patients and 100 healthy volunteers and the metabolites were analyzed by mass spectrometry. The target metabolites consisted of 23 amino acids, 26 acylcarnitines and 45 conventional blood markers. A regression analysis model was established based on 12 metabolites and five blood markers selected… More
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ARTICLE
Sinomenium Inhibits the Viability of Hepatoma Carcinoma Cells through Activating IFNA2
Jingjing He^1,2, Lingyi Zhang², Dan Guo³, Xingwen Han⁴, Hui Zhang⁵, Liang Wang², Youcheng Zhang^1,*
Oncologie, Vol.22, No.1, pp. 1-12, 2020, DOI:10.32604/oncologie.2020.012436
Abstract Hepatocellular carcinoma (HCC) ranks the sixth place of most common cancers. Meanwhile, it is the tertiary mortality cause of cancer. There is no effective therapeutic method to prevent and treat the liver cancer. Sinomenine is a kind of Chinese traditional medicine herbal, it is reported that it can inhibit the viability of several cancer cells. The study is to explore whether sinomenine is also able to inhibit the cell viability of HCC and its potential mechanism. The IC50 of sinomenine in BEL-7402 cells was 5.351 mmol/L, and the IC50 of sinomenine in SMMC-7721 cells was 6.204 mmol/L. The gene expression… More
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ARTICLE
Expression Changes, Prognostic Analysis and Risk Factors of miR-625-3p and miR-449a in Osteosarcoma Patients after Surgery
Hui Zhang, Zhan Wang, Lin Liu, Fuqiang Zhang, Yuxin Song, Yaowen Qian^*
Oncologie, Vol.22, No.1, pp. 23-33, 2020, DOI:10.32604/oncologie.2020.012493
Abstract The expression changes of miR-625-3p and miR-449a in osteosarcoma patients after surgery is the critical study in this paper. Analysis of their prognosis and risk factors can be helpful in understanding the prognostic value for clinical purposes. Fifty-eight patients with osteosarcoma diagnosed in our hospital were considered as the research group (RG), and 52 health subjects at the same time were collected as the control group (CG). Fluorescence quantitative PCR (RTPCR) was employed to test the expression levels of miR-625-3p and miR-449a in the serum of subjects in both groups before surgery and patients in the RG after surgery. The… More
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