Hydrogels with Brain Tissue-Like Mechanical Properties in Complex Environments
Jingyu Wang1,#, Yongrou Zhang4,#, Zuyue Lei1, Junqi Wang1, Yangming Zhao1, Taolin Sun3,*, Zhenyu Jiang1, Licheng Zhou1, Zejia Liu1, Yiping Liu1, Bao Yang1, Liqun Tang1,2,*
The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2022.08829
Abstract In surgical training applications and experimental research, brain tissues immersed in cerebrospinal fluid
often involve very complex deformation and strain rate effects, which affects their reliability and stability.
Thus, it is indispensable to develop a high-fidelity human brain tissue simulant material as a physical
surrogate model to understand their mechanical behavior, such as traumatic brain injury (TBI). However,
the reported simulant materials have not yet been able to compare and satisfy the above two mechanical
properties. Here, we developed a novel composite hydrogel with brain tissue-like mechanical properties and
investigated their mechanical behavior in a… More >