Open Access

ARTICLE

KRIGING SURROGATE BASED OPTIMIZATION OF THERMAL DAMAGE TO LIVING BIOLOGICAL TISSUES BY LASER IRRADIATION BASED ON A GENERALIZED DUAL PHASE LAG MODEL

Nazia Afrin^a,*, Jonathan Lopez, Juan Ocampo

a Department of Mechanical Engineering, St. Mary’s University, One Camino Santa Maria, San Antonio 78228
*Corresponding author. Email: nafrin@stmarytx.edu

Frontiers in Heat and Mass Transfer 2022, 18, 1-7. https://doi.org/10.5098/hmt.18.46

Abstract

Large number of numerical computer simulations in engineering places is a serious burden on associated optimization problems nowadays. Kriging Surrogate based optimization (KSBO) becomes standard practice in analyzing expensive and time-consuming simulation. This paper aims to investigate the surrogate based analyze and optimization of thermal damage in living biological tissue by laser irradiation using a generalized duel phase model. The relationships of maximum temperature and thermal damage in living biological tissues of the response with two variables at a time are studied. The result shows that the surrogate model predicted response variables i.e, temperature and thermal damage are in good agreement with the original values. This result will help to predict the thermal damage and temperature of living tissue without solving the large numeric computer simulation rather using surrogate kriging model.

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