Special Issue "Bioheat Transfer in Micro and Macro Scales"

Submission Deadline: 30 November 2020 (closed)
Guest Editors
Prof. Ying He, Dalian University of Technology
Prof. Gang ZHAO, the University of Science and Technology of China


Heat transfer plays a vital role in living systems as it can help us in understanding of life processes. To survive in extreme thermal environment such as in deep sea or out in space, designing a special gear for safety is of importance. Heat transfer has also many therapeutic applications that involve in either raising of lowering of temperature, such as cryosurgery, hyperthermia, hypothermia, laser ablation etc. Heat transfer analysis can be used to obtain the information about the alterations of blood flow. Many new thermal analysis techniques have been developed to detect microvessel tone from skin temperature. All of the above examples are based on bioheat transfermodeling in micro and macro scales. 

The special issue is aimed at presenting the most recent developments and research efforts in the field of bioheat transfer in micro and macro scales, in order to provide the advances of scientific knowledge in this field and pave the way for innovative clinical applications of early diagnosis and treatment. 

Potential topics include, but are not limited to the following: 

* Hyper- and hypo-thermia in biology

* Biopreservation
* Thermal therapies
* Cryosurgery
* Thermal comfort of human body
* Tumor detections
* Heat transfer analysis for blood flow measurement
* Nanoparticles and magnetic hyperthermia 

Heat and mass transfer; mathematical modeling; human thermoregulation; nanoparticle; thermal measurement

Published Papers
  • A Computational Study on the Effect of Bifurcation Lesions with Different Structures on Blood Velocity and Temperature
  • Abstract Treating coronary bifurcation stenosis is still a challenging task. Existing procedures still display a relatively small rate of success. This paper aims to investigate numerically the effect of bifurcation lesions with different structures on the dynamics of blood flow and related temperature. The problem geometry is parametrically varied by changing the bifurcation angle and radius. A finite volume method is used to simulate the three-dimensional flow. The effects induced by the structure of the stenosis, the artery bifurcation angle and radius, and the inlet velocity of blood are discussed in terms of flow pattern, pressure distribution, and shear stress at… More
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  • Modeling and Simulation of a Hybrid Jet-Impingement/Micro-Channel Heat Sink
  • Abstract With the progressive increase in the number of transistors that can be accommodated on a single integrated circuit, new strategies are needed to extract heat from these devices in an efficient way. In this regard methods based on the combination of the so-called “jet impingement” and “micro-channel” approaches seem extremely promising for possible improvement and future applications in electronics as well as the aerospace and biomedical fields. In this paper, a hybrid heat sink based on these two technologies is analysed in the frame of an integrated model. Dedicated CFD simulation of the coupled flow/temperature fields and orthogonal tests are… More
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  • Improving Mechanical Properties of Vitrified Umbilical Arteries with Magnetic Warming
  • Abstract The damage caused by thermal stress during rewarming vitrified biosamples is one of the major obstacles for clinical purposes. Magnetic warming is a highly effective approach to overcome this hurdle and can achieve rapid and spatially homogeneous heating. The current research investigates the effects of magnetic warming on the histological and biomechanical properties of the vitrified umbilical arteries (UAs) through experiments and simulation. The results of experiments show that, for the case of magnetic warming comparing with the conventional water bath, magnetic warming presents better preservation of extracellular matrix (ECM), collagen fibers, elastic fibers, and muscle fibers of the umbilical… More
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  • Numerical Evaluation of Residual Water Content after Freezing during the Lyophilization of Platelets
  • Abstract Pre-freezing is an important stage in freeze-drying processes. For the lyophilization of a cell, freezing not only plays a role for primary dehydration, but it also determines the amount of residual (intracellular or extracellular) water, which in turn can influence the solution properties and the choice of operation parameters. The freezing of human platelets in lyoprotectant solution is theoretically investigated here. A two-parameter model and an Arrhenius expression are used to describe cell membrane permeability and its temperature dependency. It is assumed that the intracellular solution is composed of four components: sodium chloride, trehalose, serum protein and water, while the… More
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