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ARTICLE
Analysis of Risk Factors for Central Venous Catheter-Associated Thrombosis in Children after Congenital Heart Surgery
1 Department of Cardiothoracic Surgery, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China
2 School of Nursing, Shanghai Jiao Tong University, Shanghai, 200025, China
3 Intensive Care of Unit, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China
4 Department of Nursing, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China
* Corresponding Authors: Li Yuan. Email: ; Wenyi Luo. Email:
Congenital Heart Disease 2024, 19(6), 603-615. https://doi.org/10.32604/chd.2025.057681
Received 24 August 2024; Accepted 17 January 2025; Issue published 27 January 2025
Abstract
Objective: To investigate the status and influencing factors of central venous catheter-associated thrombosis in children after congenital heart surgery and to provide evidence for preventive measures. Methods: From January 2024 to March 2024, hospitalized children with central venous catheters (CVC) in the Shanghai Grade III Children’s Hospital intensive care unit were selected. Catheter-related thrombosis (CRT) was evaluated using bedside ultrasound technology combined with visible thrombus after CVC extraction, dividing the patients into the thrombus and non-thrombus groups. Univariate and LASSO regression analyses were used to analyze the factors influencing CRT in children after congenital heart surgery, and binary logistic regression was used to analyze the risk factors. Results: 229 children were included, of which 24 (10.48%) had CRT. Binary logistic regression analysis showed that time of vasoconstrictor use >one day, sedation and analgesia time, and flushing the CVC with saline were the risk factors for CRT in children after congenital heart surgery. Conclusion: The incidence of CRT is higher in children after congenital heart surgery. The medical staff can formulate targeted intervention measures based on the corresponding risk factors to reduce the incidence of CRT.Keywords
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