Home / Journals / CHD / Vol.19, No.5, 2024
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  • Open AccessOpen Access

    ARTICLE

    The Norwood with Blalock-Taussig-Thomas Shunt—Worth a Second Look?

    Manasa Gadiraju1,*, Dhaval Chauhan2, Alexandra Schray3, James E. O’Brien Jr.1,4, Edo Kwaku Setsoafia Bedzra1,4
    Congenital Heart Disease, Vol.19, No.5, pp. 435-443, 2024, DOI:10.32604/chd.2025.059705 - 31 December 2024
    Abstract Background: Shunt repair for the Norwood procedure with either the right ventricle to pulmonary artery shunt (RVPAS) or the modified Blalock-Taussig-Thomas Shunt (BTTS) varies by institution and surgeon preference. Shunt choice has been informed by landmark trials including the Single Ventricle Reconstruction trial and modern outcomes data may engender future complementary studies. Methods: We conducted a retrospective analysis of all patients who underwent the Norwood procedure from 2014–2022 at a single center to compare outcomes by shunt type. The primary outcome measure was freedom from death or transplant. Secondary outcome measures included hospital length of… More >

  • Open AccessOpen Access

    ARTICLE

    Long-Term Follow-Up Study on Electrophysiology Guidance for Transcatheter Closure of Perimembranous Ventricular Septal Defect in Adults

    Wenrui Li1, Nanshan Xie1, Xianzhang Zhan1, Ziyang Yang2, Hezhi Li1, Caojin Zhang1,*
    Congenital Heart Disease, Vol.19, No.5, pp. 445-455, 2024, DOI:10.32604/chd.2024.053604 - 31 December 2024
    Abstract Objectives: To explore the feasibility and efficacy of electrophysiology guidance for transcatheter closure of perimembranous ventricular septal defect (PmVSD) in adults. Methods: Adult patients with PmVSD who underwent transcatheter in Guangdong Provincial People’s Hospital, Guangdong Cardiovascular Institute from February 2016 to January 2018 were selected. The distribution of the His-Purkinje system (HPS) close to the margins of PmVSD in the left ventricle was identified using three-dimensional (3D) electro-anatomic mapping and near-field HPS was further confirmed by different pacing protocols. The follow-up protocol included electrocardiogram (ECG)and transthoracic echocardiography at 6, 24, 72 h, 1, 3, 6… More >

  • Open AccessOpen Access

    ARTICLE

    Evaluation of Post-Operative Atrial Fibrillation after Cardiac Surgery for Adult Congenital Heart Disease

    Jonathan S. Taylor-Fishwick1,*, Nicholas Holzemer2, Brandon Middlemist3, Vivian Duarte3, Kaitlin E. Olson4, Johannes C. von Alvensleben5, Megan SooHoo6, Amber Khanna7
    Congenital Heart Disease, Vol.19, No.5, pp. 457-472, 2024, DOI:10.32604/chd.2024.057151 - 31 December 2024
    Abstract Background: Post-operative atrial fibrillation (POAF) frequently occurs after cardiac surgery. Although adult congenital heart disease (ACHD) patients have higher rates of arrhythmia than the general population, there is scant literature on POAF in ACHD patients. Objectives: Identify key risk factors associated with post-operative atrial fibrillation and evaluate the short- and mid-term significance of developing POAF. Methods: A retrospective cohort study was conducted of ACHD patients from 2013–2021 at the University of Colorado Hospital and Children’s Hospital of Colorado. The institutional Society of Thoracic Surgeons (STS) surgical registry was used to identify patients ≥18-year-old with congenital heart… More >

  • Open AccessOpen Access

    ARTICLE

    Cardiac Rehabilitation by Pulmonary Artery Banding after Induced Dilated Cardiomyopathy: A Pilot Study on a Rodent Model

    Domenico Crea1, Arben Dedja1, Matteo Ponzoni1,2, Stefania Rizzo3, Alberto Cipriani4, Riccardo Bariani4, Kalliopi Pilichou3, Maria Bueno Marinas3, Danila Azzolina5, Massimo A. Padalino1,6,*
    Congenital Heart Disease, Vol.19, No.5, pp. 473-487, 2024, DOI:10.32604/chd.2025.057014 - 31 December 2024
    Abstract Background: Since 2015, the pulmonary artery banding (PAB), following the Giessen protocol, has treated end-stage heart failure in selected infants with preserved right ventricular function, acting as a bridge to transplant or recovery, as a result of ventricular-ventricular interaction. Objectives: To elucidate whether PAB is a feasible and reproducible procedure in a rodent model of pharmacologically induced dilated cardiomyopathy (DCM) and to evaluate PAB-induced ventricular rehabilitation. Methods: We used 49 Sprague-Dawley rats divided into four groups: a sham surgery control group, a healthy animal group undergoing PAB, a doxorubicin (DOX)- treated control group, and a DOX… More >

  • Open AccessOpen Access

    ARTICLE

    Efficacy of Intravenous Treprostinil in High-Risk Single Ventricle Patients Undergoing Glenn Procedure

    Xiaofeng Wang1,#, Xingwei Chen2,#, Shilin Wang1, Xia Li1, Zhongyuan Lu1, Wenlong Wang1, Xu Wang1,*
    Congenital Heart Disease, Vol.19, No.5, pp. 489-498, 2024, DOI:10.32604/chd.2024.054441 - 31 December 2024
    Abstract Objective: Pulmonary hypertension is a crucial factor affecting the recovery after Glenn procedure. This study explores the effects of intravenous treprostinil on hemodynamic status and hospital postoperative recovery under different administration strategies. Methods: We retrospectively included pediatric patients admitted to Fuwai Hospital from 2019 to 2022 who underwent the Glenn procedure and had intraoperative measurements of mean pulmonary artery pressure (mPAP) >15 mmHg postoperatively. Patients with non-anatomical single ventricle physiology undergoing the Glenn procedure and those requiring postoperative extracorporeal membrane oxygenation were excluded. Due to the standardized use of treprostinil in our center starting in… More >

  • Open AccessOpen Access

    REVIEW

    Unmet Needs in Pediatric and Congenital Heart Surgery: A Review

    Dominique Vervoort1,2,*, Mimi X. Deng2,3, Aliya Izumi4, Shelby Kutty5, Frank Edwin6,7
    Congenital Heart Disease, Vol.19, No.5, pp. 499-511, 2024, DOI:10.32604/chd.2024.057749 - 31 December 2024
    Abstract Pediatric and congenital heart disease (PCHD) affects millions of children worldwide, including over one million babies born with congenital heart disease (CHD) each year and 300,000 children dying from rheumatic heart disease (RHD) yearly. Although the vast majority of children born with CHD in high-income countries now reach adulthood and RHD is nearly eradicated in these countries, most of the world cannot access the necessary care to prevent or mitigate PCHD. In low- and middle-income countries, over 90% of children with PCHD cannot receive the care they need, as over 100 countries and territories… More >

  • Open AccessOpen Access

    REVIEW

    Transcatheter Pulmonary Valve Implantation: A State of the Art Review

    Biagio Castaldi1,*, Francesco Prati1, Alice Pozza1,2, Irene Cattapan1,2, Jennifer Fumanelli1,2, Domenico Sirico1, Giovanni Di Salvo1
    Congenital Heart Disease, Vol.19, No.5, pp. 513-533, 2024, DOI:10.32604/chd.2025.058053 - 31 December 2024
    Abstract Congenital heart disease (CHD) affects about 1% of live births. Among them, about 20% will undergo one or more surgical or percutaneous maneuvers on the right ventricle outflow tract or pulmonary valve. Transcatheter pulmonary valve implantation is a recently available less invasive alternative to surgery for treatment of right ventricular outflow tract dysfunction. Thus, residual dysfunction can be treated early and with a lower risk profile. This narrative review aimed to describe the state of the art of percutaneous pulmonary valve implantation. More >

  • Open AccessOpen Access

    LETTER

    Hybrid Procedure for Interruption of Aortic Arch Associated with Bicuspid Aortic Valve Stenosis in an Infant

    Jiajun Xu1,#, Zhuo Shi2,#, Shanshan Shi1,*, Xiangming Fan2,*
    Congenital Heart Disease, Vol.19, No.5, pp. 535-540, 2024, DOI:10.32604/chd.2024.057558 - 31 December 2024
    Abstract Interrupted Aortic Arch (IAA) combined with aortic stenosis (AS) is a rare and complex congenital cardiac anomaly that presents significant challenges in clinical management. In this letter, we aim to share our experience in performing hybrid procedures on an infant diagnosed with IAA combined with bicuspid AS. This child exhibited significant recovery during follow-up. More >

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