Open Access

ARTICLE

Ryan G. McQueen¹, Nikki M. Singh², Ronald K. Woods^3,*
Congenital Heart Disease, Vol.19, No.3, pp. 257-266, 2024, DOI:10.32604/chd.2024.052108
Abstract Objective: The objective of this study was to compare cardiac transplant operative and postoperative courses of patients with failed Fontan physiology who were initially palliated with a Norwood (FFN) to those without a prior Norwood (FF). Methods: A single-institution retrospective review of all patients with Fontan failure who underwent cardiac transplantation from 2003–2021 was completed—22 underwent prior Norwood (FFN) and 11 did not (FF). Descriptive and inferential statistics were calculated for operative course and patient outcomes. Results: The operative course of the FFN cohort appeared to be more complex (not statistically significant, but clinically relevant)—this group… More >

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CASE REPORT

Sherif Negm^1,2, Loic Mace¹, Fedoua El Louali³, Beatrice Desnous⁴, Philipe Aldebert³, Virginie Fouilloux¹, Marien Lenoir^1,*
Congenital Heart Disease, Vol.19, No.3, pp. 267-273, 2024, DOI:10.32604/chd.2024.051642
Abstract The aorto-ventricular tunnel is a rare congenital cardiac anomaly. We present a case of aorto-ventricular tunnel diagnosed via fetal echocardiography. Emergency surgery was performed on the 2nd day of life to close the tunnel, located just in front of the right coronary ostium, due to the patient’s unstable health condition. The postoperative period revealed complete occlusion of the right coronary artery. Due to the patient’s stability, we opted not to reintervene on the right coronary artery. The patient fully recovered without the need for further coronary intervention. In cases of patients with an aorto-ventricular tunnel More >

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CASE REPORT

Qiqi Shi^1,#, Xuan Lei^2,#, Wenbo Zhang^1,*, Ming Ye^1,*
Congenital Heart Disease, Vol.19, No.3, pp. 275-278, 2024, DOI:10.32604/chd.2024.051370
Abstract Introduction: Transposition of the great arteries (TGA) with aortopulmonary window is a rare type of congenital heart disease with limited experience. We reported a neonate aged 25 days receiving the arterial switch operation and assisted with extracorporeal membrane oxygenation. Conclusion: TGA with aortopulmonary window can be safely correctly with the arterial switch operation. More >

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ARTICLE

Yang Hua^#, Jinyu Sun^#, Yuxuan Lou, Hao Zhang, Jing Shi^*, Wei Sun^*
Congenital Heart Disease, Vol.19, No.3, pp. 279-291, 2024, DOI:10.32604/chd.2024.051190
Abstract Background: White matter lesion (WML) is common in aging brain and is associated with cognitive impairment and dementia. However, recent studies reported an association between patent foramen ovale (PFO) and WML in migraineurs, especially in young, middle-aged migraineurs. Our retrospective, case-control study aims to describe the clinical characteristics of WML in this population and to explore potential risk factors. Methods: 226 patients with migraine and PFO were consecutively initially screened. Relevant factors were selected by the least absolute shrinkage and selection operator (LASSO) regression and multivariable logistic regression model. A Nomogram was employed to visualize… More >

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ARTICLE

Jiawang Xiao, Jianming Wang, Zhongchao Wang, Lili Meng, Ming Zhao, Qiguang Wang^*
Congenital Heart Disease, Vol.19, No.3, pp. 293-303, 2024, DOI:10.32604/chd.2024.051427
Abstract Background: Transcatheter closure (TCC) has emerged as the preferred treatment for selected congenital heart disease (CHD). While TCC offers benefits for patients with postoperative residual shunts, understanding its mid- and long-term efficacy and safety remains crucial. Objective: This study aims to assess the mid- and long-term safety and efficacy of TCC for patients with residual atrial or ventricular septal shunts following CHD correction. Methods: In this consecutive retrospective study, we enrolled 35 patients with residual shunt who underwent TCC or surgical repair of CHD between June 2011 to October 2022. TCC candidacy was determined based on… More >

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REVIEW

Marcio Fragoso Vieira^1,2, Nathalie Jeanne Bravo-Valenzuela³, Edward Araujo Júnior^1,*
Congenital Heart Disease, Vol.19, No.3, pp. 305-314, 2024, DOI:10.32604/chd.2024.053484
Abstract Congenital heart disease (CHD) is the most common type of birth defect, representing a significant cause of perinatal morbidity and mortality. Early diagnosis of such anomalies is crucial for improving outcomes. Current protocols recommend a qualitative assessment of cardiac structures using two-dimensional ultrasound (2DUS) and color Doppler imaging. In cases of suspected abnormalities, quantitative assessments through cardiac structure measurements and reference curves can aid in accurate diagnosis. Similar to centiles widely employed in obstetrics, Z-scores provide more precise quantification of various cardiac structures, particularly at the extremes of the curve. While the development of reference More >

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ARTICLE

Risalina Myrtha^1,2,*, Hasanah Mumpuni^3,4, Real Kusumanjaya Marsam^3,4, Dyah Wulan Anggrahini^3,4, Anggoro Budi Hartopo^3,4, Lucia Kris Dinarti^3,4
Congenital Heart Disease, Vol.19, No.3, pp. 315-324, 2024, DOI:10.32604/chd.2024.051587
Abstract Background and Objective: The most feared complication of uncorrected secundum Atrial Septal Defect (ASD) is pulmonary arterial hypertension (PAH). Pulmonary vascular resistance (PVR) is crucial in detecting precapillary pulmonary hypertension (PH) to guide the need for PAH-specific therapy. There is a change in the cut-off value of PVR according to the recently updated PH guideline. How echocardiographic PVR (PVR) correlates to PVR by right heart catheterization (RHC) (PVR) according to the new guidelines has not been known. The aim of this study is to determine the reliability of PVR in detecting PAH in Uncorrected Ostium… More >

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ARTICLE

Wenjie Dong^1,2,#, Zhibin Hong^1,#, Aqian Wang², Kaiyu Jiang², Hai Zhu², Fu zhang², Zhaoxia Guo², Hongling Su^2,*, Yunshan Cao^3,*
Congenital Heart Disease, Vol.19, No.3, pp. 325-339, 2024, DOI:10.32604/chd.2024.052267
（This article belongs to the Special Issue: Interventional therapy of congenital heart disease: past, now, and future)
Abstract Background: Current guidelines for managing pulmonary arterial hypertension (PAH) recommend a risk stratification approach. However, the applicability and accuracy of these strategies for PAH associated with congenital heart disease (PAH-CHD) require further validation. This study aims to validate the reliability and predictive accuracy of a simplified stratification strategy for PAH-CHD patients over a three-year follow-up. Additionally, new prognostic variables are identified and novel risk stratification methods are developed for assessing and managing PAH-CHD patients. Methods: This retrospective study included 126 PAH-CHD patients. Clinical and biochemical variables across risk groups were assessed using Kruskal-Wallis and Fisher’s… More >

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