TY - EJOU
AU - Pang, Tong
AU - Jiang, Li
AU - Zhang, Yi
AU - Yang, Mengxi
AU - Wang, Jin
AU - Li, Yuan
AU - Yang, Zhigang
TI - Comparison of Intracardiac and Extracardiac Malformations Associated with Single Atrium, Single Ventricle and Single Atrium-Single Ventricle Using DualSource Computed Tomography
T2 - Congenital Heart Disease
PY - 2022
VL - 17
IS - 4
SN - 1747-0803
AB - Background: To evaluate the qualitative and quantitative differences between intracardiac and extracardiac vascular malformations in patients with a single atrium (SA), single ventricle (SV) and single atrium-single ventricle
(SA-SV) using dual-source CT (DSCT), and to compare the diagnostic performances of DSCT and transthoracic
echocardiography (TTE). Methods: This retrospective study included 24 SA, 75 SV and 24 SA-SV patients who
underwent both DSCT and TTE before surgery. The diagnostic values of DSCT and TTE for intracardiac and
extracardiac malformations were compared according to the surgical results. The diameters of the major artery
and vein were measured and calculated based on DSCT and compared among the three groups. Results: The
most common malformation was pulmonary artery disease in SA (50.0%) and SA-SV (45.8%) groups and patent
ductus arteriosus (33.3%) in SV group. Although there was no statistical difference, arterial development was relatively poor in the SA group. All groups showed the trend of pulmonary artery stenosis (SAvs. SVvs. SA-SV: 50.0%
vs. 30.7% vs. 33.3%). There was a significant difference in mean pulmonary vein index among the groups
(p = 0.017). The diagnostic sensitivity of DSCT was superior to that of TTE for extracardiac malformations. Conclusions: The most common malformation in SA and SA-SV patients is pulmonary artery stenosis. SV patients
are most likely to be complicated with patent ductus arteriosus. DSCT is more advantageous than TTE for diagnosing combined extracardiac malformations and can accurately measure the diameter of arteriovenous vessels.
KW - Single atrium; single ventricle; computed tomography; congenital heart disease
DO - 10.32604/chd.2022.020401