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Comparison of Intracardiac and Extracardiac Malformations Associated with Single Atrium, Single Ventricle and Single Atrium-Single Ventricle Using DualSource Computed Tomography

Tong Pang#, Li Jiang#, Yi Zhang, Mengxi Yang, Jin Wang, Yuan Li*, Zhigang Yang*
Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China
* Corresponding Authors: Zhigang Yang. Email: ; Yuan Li. Email:
# These authors equally contributed to this work as first author

Congenital Heart Disease 2022, 17(4), 479-489. https://doi.org/10.32604/chd.2022.020401

Received 22 December 2021; Accepted 10 March 2022; Issue published 04 July 2022

Abstract

Background: To evaluate the qualitative and quantitative differences between intracardiac and extracardiac vascular malformations in patients with a single atrium (SA), single ventricle (SV) and single atrium-single ventricle (SA-SV) using dual-source CT (DSCT), and to compare the diagnostic performances of DSCT and transthoracic echocardiography (TTE). Methods: This retrospective study included 24 SA, 75 SV and 24 SA-SV patients who underwent both DSCT and TTE before surgery. The diagnostic values of DSCT and TTE for intracardiac and extracardiac malformations were compared according to the surgical results. The diameters of the major artery and vein were measured and calculated based on DSCT and compared among the three groups. Results: The most common malformation was pulmonary artery disease in SA (50.0%) and SA-SV (45.8%) groups and patent ductus arteriosus (33.3%) in SV group. Although there was no statistical difference, arterial development was relatively poor in the SA group. All groups showed the trend of pulmonary artery stenosis (SAvs. SVvs. SA-SV: 50.0% vs. 30.7% vs. 33.3%). There was a significant difference in mean pulmonary vein index among the groups (p = 0.017). The diagnostic sensitivity of DSCT was superior to that of TTE for extracardiac malformations. Conclusions: The most common malformation in SA and SA-SV patients is pulmonary artery stenosis. SV patients are most likely to be complicated with patent ductus arteriosus. DSCT is more advantageous than TTE for diagnosing combined extracardiac malformations and can accurately measure the diameter of arteriovenous vessels.

Keywords

Single atrium; single ventricle; computed tomography; congenital heart disease

Cite This Article

Pang, T., Jiang, L., Zhang, Y., Yang, M., Wang, J. et al. (2022). Comparison of Intracardiac and Extracardiac Malformations Associated with Single Atrium, Single Ventricle and Single Atrium-Single Ventricle Using DualSource Computed Tomography. Congenital Heart Disease, 17(4), 479–489.



This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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