Open Access iconOpen Access

ARTICLE

Adults with Congenital Heart Disease during the COVID-19 Era: One-Year Tertiary Center Experience

Fatma A. Taha1,2,*, Osama Amoudi1, Fareed Alnozha1, Reda Abuelatta1

1 Adult Cardiology Department, Madinah Cardiac Center, Madinah, Saudi Arabia
2 Cardiology Department, Faculty of Medicine, Tanta University, Tanta, Egypt

* Corresponding Author: Fatma A. Taha. Email: email

Congenital Heart Disease 2022, 17(4), 399-419. https://doi.org/10.32604/chd.2022.020174

Abstract

Background: Adult patients with congenital heart disease (ACHD) might be at high risk of Coronavirus disease- 2019 (COVID-19). This study aimed to report on a one-year tertiary center experience regards COVID-19 infection in ACHD patients. Methods: This is a one-year (March-2020 to March-2021) tertiary-center retrospective study that enrolled all ACHD patients; COVID-19 positive patients’ medical records, and management were reported. Results: We recorded 542 patients, 205 (37.8%) COVID-19-positive, and 337 (62.2%) COVID-19-negative patients. Palliated single ventricle and Eisenmenger syndrome patients were more vulnerable to COVID-19 infection (P < 0.05*). Cardiovascular COVID-19 complications were arrhythmias in 47 (22.9%) patients, heart failure in 39 (19.0%) patients, cyanosis in 12 (5.9%) patients, stroke/TIA in 5 (2.4%) patients, hypertension and infective endocarditis in 2 (1.0%) patients for each, pulmonary hypertension and pulmonary embolism in 1 (0.5%) patient for each. 11 (5.4%) patients were managed with home isolation, 147 (71.7%) patients required antibiotics, 32 (15.6%) patients required intensive care unit (ICU), 8 (3.9%) patients required inotropes, 7 (3.4%) patients required mechanical ventilation, and 2 (1.0%) patients required extracorporeal membrane oxygenation (ECMO). Thromboprophylaxis was given to all 46 (22.4%) hospitalized patients. American College of Cardiology/American Heart Association classification revealed that complex lesions, and FC-C/D categories were more likely to develop severe/critical symptoms, that required mechanical ventilation and ECMO (P < 0.05*). Mortality was reported in 3 (0.6%) patients with no difference between groups (P = 0.872). 193 (35.6%) patients were vaccinated. Conclusions: COVID-19 infection in ACHD patients require individualized risk stratification and management. Eisenmenger syndrome, single ventricle palliation, complex lesions, and FC-C/D patients were more vulnerable to severe/critical symptoms that required ICU admission, mechanical ventilation, and ECMO. The vaccine was mostly tolerable.

Keywords


Cite This Article

APA Style
Taha, F.A., Amoudi, O., Alnozha, F., Abuelatta, R. (2022). Adults with congenital heart disease during the COVID-19 era: one-year tertiary center experience. Congenital Heart Disease, 17(4), 399-419. https://doi.org/10.32604/chd.2022.020174
Vancouver Style
Taha FA, Amoudi O, Alnozha F, Abuelatta R. Adults with congenital heart disease during the COVID-19 era: one-year tertiary center experience. Congeni Heart Dis. 2022;17(4):399-419 https://doi.org/10.32604/chd.2022.020174
IEEE Style
F.A. Taha, O. Amoudi, F. Alnozha, and R. Abuelatta, “Adults with Congenital Heart Disease during the COVID-19 Era: One-Year Tertiary Center Experience,” Congeni. Heart Dis., vol. 17, no. 4, pp. 399-419, 2022. https://doi.org/10.32604/chd.2022.020174



cc Copyright © 2022 The Author(s). Published by Tech Science Press.
This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 1674

    View

  • 720

    Download

  • 1

    Like

Share Link