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Alberto Cipriani^1,#, Pietro Bernardo Dall’Aglio^1,#, Laura Mazzotta¹, Domenico Sirico², George Sarris³, Mark Hazekamp⁴, Thierry Carrel⁵, Alessandro Frigiola⁶, Vladimir Sojak⁴, Mauro Lo Rito⁶, Jurgen Horer⁷, Regine Roussin⁷, Julie Cleuziou⁸, Bart Meyns⁹, Jose Fragata¹⁰, Helena Telles¹⁰, Anastasios C. Polimenakos¹¹, Katrien Francois¹², Altin Veshti¹³, Jukka Salminen¹⁴, Alvaro Gonzalez Rocafort¹⁵, Matej Nosal¹⁶, Eleftherios Protopapas³, Roberto Tumbarello¹⁷, Patrizio Sarto¹⁸, Cinzia Pegoraro¹⁸, Raffaella Motta¹⁹, Giovanni Di Salvo², Domenico Corrado¹, Vladimiro L. Vida¹, Massimo A. Padalino^1,2,*
Congenital Heart Disease, Vol.17, No.4, pp. 375-385, 2022, DOI:10.32604/chd.2022.019385
Abstract Background: Anomalous aortic origin of a coronary artery (AAOCA) is a congenital heart disease with a 0.3%−0.5% prevalence. Diagnosis is challenging due to nonspecific clinical presentation. Risk stratification and treatment are currently based on expert consensus and single-center case series. Methods: Demographical and clinical data of AAOCA patients from 17 tertiary-care centers were analyzed. Diagnostic imaging studies (Bidimensional echocardiography, coronary computed tomography angiography [CCTA] were collected. Clinical correlations with anomalous coronary course and origin were evaluated. Results: Data from 239 patients (42% males, mean age 15 y) affected by AAOCA were collected; 154 had AAOCA involving the right coronary artery… More >

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Gregory Perens^1,*, Takegawa Yoshida², J. Paul Finn²
Congenital Heart Disease, Vol.17, No.4, pp. 387-392, 2022, DOI:10.32604/chd.2022.021233
Abstract An infant male presented with the rare anatomy consisting of situs solitus, concordant atrioventricular connections to L-looped ventricles, double outlet right ventricle (DORV), and hypoplastic aortic arch. 6 months after neonatal aortic arch repair, the morphologic right ventricle function deteriorated, and surgical evaluation was undertaken to determine if either biventricular repair with a systemic morphologic left ventricle or right ventricular exclusion was possible. After initial echocardiography, magnetic resonance imaging (MRI) was used to create detailed axial and 4-dimensional (4D) images and 3-dimensional (3D) printed models. The detailed anatomy of this rare, complex case and its use in pre-surgical planning is… More >

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Mi Kyoung Song¹, Gi Beom Kim¹, Woong Han Kim², Whal Lee³, Eun-Jung Bae^1,*
Congenital Heart Disease, Vol.17, No.4, pp. 393-398, 2022, DOI:10.32604/chd.2022.019603
Abstract We report the case of a rare complex cardiac anomaly involving situs solitus, concordant atrioventricular connection with left-hand ventricular topology, and L-looped ventricles. The ventricles had a superior-inferior relationship with an inferiorly located right ventricle, which had a double outlet with far posteriorly located great arteries. The left atrium was elongated, with juxta-positioned atrial appendages on the right side. The 3D-printed model using a computed tomography scan taken on the fourth day of birth demonstrated the anatomy clearly and helped us decide on the surgical management. More >

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ARTICLE

Fatma A. Taha^1,2,*, Osama Amoudi¹, Fareed Alnozha¹, Reda Abuelatta¹
Congenital Heart Disease, Vol.17, No.4, pp. 399-419, 2022, DOI:10.32604/chd.2022.020174
Abstract Background: Adult patients with congenital heart disease (ACHD) might be at high risk of Coronavirus disease- 2019 (COVID-19). This study aimed to report on a one-year tertiary center experience regards COVID-19 infection in ACHD patients. Methods: This is a one-year (March-2020 to March-2021) tertiary-center retrospective study that enrolled all ACHD patients; COVID-19 positive patients’ medical records, and management were reported. Results: We recorded 542 patients, 205 (37.8%) COVID-19-positive, and 337 (62.2%) COVID-19-negative patients. Palliated single ventricle and Eisenmenger syndrome patients were more vulnerable to COVID-19 infection (P < 0.05*). Cardiovascular COVID-19 complications were arrhythmias in 47 (22.9%) patients, heart failure… More >

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Hugues Lucron^1,*, Alban-Elouen Baruteau^2,3, Caroline Ovaert⁴, Ali Houeijeh⁵, Mélanie Brard¹, Patrice Guerin², François Bourlon⁶, Claire Dauphin⁷, Saskia Tuttle¹, Maha Tagorti³, Rishika Banydeen⁸, François Godart⁵
Congenital Heart Disease, Vol.17, No.4, pp. 421-436, 2022, DOI:10.32604/chd.2022.020835
Abstract Objectives: We aim to describe the efficacy, safety, and characteristics of the Amplatzer Vascular Plug (AVP) II and IV “off-label” use for multiple cardiovascular occlusions in children under 10 years. Methods: Observational retrospective multicenter (2007–2020, 6 centers) review of paediatric procedures using AVP II or IV. Results: A total of 125 children (49.6% aged ≤ 1 year, 147 lesions) underwent 136 successive procedures (success rate: 98.5%) using 169 devices (109 AVP IV, 60 AVP II). The mean device diameter was 7.7 ± 3.2 mm (4–20 mm). The median AVP size to vessel diameter ratio was 1.3 (0–2). The median age and weight… More >

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Shibin Sun^1,#, Geoffrey J. Changwe^1,2,#, Zeeshan Farhaj¹, Hongxin Li^1,*, Yuekun Sun¹, Zhongzheng Kong¹
Congenital Heart Disease, Vol.17, No.4, pp. 437-445, 2022, DOI:10.32604/chd.2022.019943
Abstract Background: Closure of large patent ductus arteriosus (PDA) in older children has been accomplished using surgical and percutaneous techniques with remarkable outcomes. However, outcomes amongst infants have been variable with several drawbacks. Here we describe a novel minimally invasive technique, a product of mini-thoracotomy and traditional percutaneous technique skills, accomplished exclusively under echocardiography guidance. Methods: Symptomatic infants with a significant left-to-right shunt from PDA measuring more than 4 mm were selected. The symptoms were varying degrees of tachypnea, tachycardia, heart failure, failure to thrive, recurrent respiratory tract infections, or intensive care unit treatment for a longer duration. Through a left… More >

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Eszter Vojcek^1,2,*, V. Anna Gyarmathy^3,4, Rozsa Graf⁵, Anna M. Laszlo⁶, Laszlo Ablonczy⁷, Zsolt Prodan⁷, Istvan Seri^1,8
Congenital Heart Disease, Vol.17, No.4, pp. 447-461, 2022, DOI:10.32604/chd.2022.022274
Abstract Objective: Neonates with congenital heart disease (CHD) and perinatal stroke have high mortality and survivors are at risk for poor long-term neurodevelopmental outcome. The aim of this study was to assess the risk factors and outcome of neonates with both CHD and MRI-confirmed perinatal stroke (Study Group) and compare those to the risk factors and outcome of infants matched for CHD without stroke (Control-1) and of infants matched for MRI-confirmed stroke without CHD (Control-2). Methods: We conducted a population-based case-control study enrolling 28 term neonates with CHD and MRI-confirmed acute perinatal stroke born between 2007–2017 in the Central-Hungarian Region. Each… More >

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Pornrawee Plearntummakun¹, Chodchanok Vijarnsorn^1,*, Kritvikrom Durongpisitkul¹, Prakul Chanthong¹, Paweena Chungsomprasong¹, Supaluck Kanjanauthai¹, Thita Pacharapakornpong¹, Jarupim Soongswang¹, Thaworn Subtaweesin²
Congenital Heart Disease, Vol.17, No.4, pp. 463-478, 2022, DOI:10.32604/chd.2022.021545
Abstract Background: Congenital coronary artery fistula (CCAF) is a rare anomaly. Treatment strategies tend to close the defect with a symptomatic and significant shunt, primarily based on expert consensus and case series. Results for long-term follow-up in children are limited Methods: We conducted a retrospective study to assess clinical and imaging outcomes of children with CCAF at Siriraj Hospital, Thailand during 2000–2020. Patients with single ventricle were excluded. Treatment strategies [surgical closure (SC), and percutaneous closure (PC)] were classified and the clinical outcomes at the follow-up in 2021, including coronary thrombosis, myocardial ischemia, and the results of cardiovascular imaging were reviewed.… More >

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Tong Pang^#, Li Jiang^#, Yi Zhang, Mengxi Yang, Jin Wang, Yuan Li^*, Zhigang Yang^*
Congenital Heart Disease, Vol.17, No.4, pp. 479-489, 2022, DOI:10.32604/chd.2022.020401
Abstract Background: To evaluate the qualitative and quantitative differences between intracardiac and extracardiac vascular malformations in patients with a single atrium (SA), single ventricle (SV) and single atrium-single ventricle (SA-SV) using dual-source CT (DSCT), and to compare the diagnostic performances of DSCT and transthoracic echocardiography (TTE). Methods: This retrospective study included 24 SA, 75 SV and 24 SA-SV patients who underwent both DSCT and TTE before surgery. The diagnostic values of DSCT and TTE for intracardiac and extracardiac malformations were compared according to the surgical results. The diameters of the major artery and vein were measured and calculated based on DSCT… More >

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Federica Caldaroni¹, Massimo Chessa², Alessandro Varrica¹, Alessandro Giamberti^1,*
Congenital Heart Disease, Vol.17, No.4, pp. 491-494, 2022, DOI:10.32604/chd.2022.019119
Abstract Multimodal imaging, including augmented or mixed reality, transforms the physicians’ interaction with clinical imaging, allowing more accurate data interpretation, better spatial resolution, and depth perception of the patient’s anatomy. We successfully overlay 3D holographic visualization to magnetic resonance imaging images for preoperative decision making of a complex case of cardiac tumour in a 7-year-old girl. More >

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