Open Access
ARTICLE
Shengwen Guo, Yuanyuan Tong, Liting Bai, Peiyao Zhang, Xin Duan*, Jinping Liu*
Congenital Heart Disease, Vol.15, No.5, pp. 275-285, 2020, DOI:10.32604/CHD.2020.011894
Abstract Objective: Serum ferritin has been identified as a prognostic marker in
patients with a variety of diseases. In the present study we aim to determine the
prevalence of risk factors and outcomes for hyperferritinemia in children undergoing cardiac surgery with cardiopulmonary bypass for congenital heart defects.
Methods: The serum ferritin levels of 457 children between the ages of twentyeight days and three years undergoing cardiopulmonary bypass surgery between
June 1, 2017 and June 1, 2018 were analyzed. The prevalence of early postoperative hyperferritinemia was investigated; hyperferritinemia was defined as a ferritin
level ≥250 ng/ml. Multivariable regression models including candidate risk… More >
Open Access
ARTICLE
Gustaf Tanghöj1,*, Anna Lindam2, Petru Liuba3,4, Gunnar Sjöberg5, Estelle Naumburg1
Congenital Heart Disease, Vol.15, No.5, pp. 287-299, 2020, DOI:10.32604/CHD.2020.011977
Abstract Objective: Secundum atrial septal defect (ASD II) is a common congenital heart defect, and interatrial communications among preterm children is
even more common. The objective of this study was to calculate the incidence
of ASD II in children, with assessment to gestational age at birth. Further, to
assess maternal, prenatal and postnatal risk factors associated with ASD II among
children of different gestational age at birth. Design: This national registry based
retrospective incidence study was supplemented with a national case-control
study, using the Swedish Register of Congenial Heart Disease, Swedish Medical
Birth Register and Statistics Sweden. All children, 0–18 years… More >
Open Access
ARTICLE
Flavia M. Wehrle1,2,3, Markus A. Landolt3,4,5, Beatrice Latal1,3, Sarah Rometsch6, Matthias Greutmann7,*
Congenital Heart Disease, Vol.15, No.5, pp. 301-308, 2020, DOI:10.32604/CHD.2020.013078
Abstract Background: The risk for a severe disease course in case of infection
with SARS-CoV-2 in young adults with congenital heart disease is largely
unknown, potentially leading to uncertainty and anxiety among affected patients.
This study aims to investigate health-related concerns, health-related quality of
life and psychological adjustment in patients with congenital heart disease compared to healthy peers during the COVID-19 pandemic. Methods: One-hundred
patients with congenital heart disease and 50 controls (M = 29.7, SD = 3.8 years)
were recruited. They completed an online survey including the assessment of
health-related concerns regarding COVID-19, the 12-item Short Form Health Survey and… More >
Open Access
ARTICLE
Francisco Javier Ruperti-Repilado1,#,*, Magalie Ladouceur2,#, Pastora Gallego3, Laura Dos4, Joaquin Rueda Soriano5, Berto Bouma6, Harald Gabriel7, Markus Schwerzmann1, Judith Bouchardy8,9, Daniel Tobler10,#, Matthias Greutmann11,#
Congenital Heart Disease, Vol.15, No.5, pp. 309-338, 2020, DOI:10.32604/CHD.2020.012599
Abstract Background: Long-term outcomes in adults with prior arterial switch
operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively
followed cohort of adults after their ASO. Methods: The comprehensive longterm follow up of adults with ASO is a project within the European collaboration
for prospective outcome research in congenital heart disease (EPOCH). It is
designed as a prospective, international multicenter cohort study. Consecutive
patients (age ≥ 16 years) with prior ASO will be included at 11 European tertiary
care centers. Participants will be followed… More >
Open Access
REVIEW
Kinjal Parikh1,2,*, Juan Carlos Muniz1,2, Elizabeth Welch1,2, Abdul Aldousany1,3, Nao Sasaki1,2
Congenital Heart Disease, Vol.15, No.5, pp. 339-346, 2020, DOI:10.32604/CHD.2020.012910
Abstract This is a newborn male prenatally diagnosed with severe right ventricular (RV) hypertrophy and depressed function, aneurysmal dilation of the main
pulmonary artery and tachyarrhythmia. Postnatally, he required immediate intubation and inotropic support. Echocardiogram revealed a large dysplastic RV, absent
pulmonary valve syndrome (APVS), markedly dilated pulmonary arteries and tricuspid atresia (TA). The trabecular portion of the RV was excessively trabeculated
and severely dilated. Inflow and infundibular walls were thin, with multiple infundibular aneurysms. There was APVS with free regurgitation and massively dilated
pulmonary arteries. The RV bulged into the LV, though there was no outflow tract
obstruction. The LV… More >
Open Access
ARTICLE
Biagio Castaldi1,*, Giulio Cabrelle1, Massimo Padalino2, Vladimiro Vida2, Ornella Milanesi1, Giovanni Di Salvo1
Congenital Heart Disease, Vol.15, No.5, pp. 347-360, 2020, DOI:10.32604/CHD.2020.012750
Abstract Background: Trans-catheter closure has become the treatment of
choice for patent foramen ovale (PFO) and ostium secundum atrial septal defects
(ASD). A wide variety of devices are commercially available, however, concerns
have been raised about the risk of cardiac erosion associated with stiff/rigid
devices. The GORE® CARDIOFORM Septal Occluder (GSO) is a double-disc,
soft and conformable device with no reported incidence of cardiac erosions. However, wire frame fracture (WFF) have been reported. Aim: To assess the incidence
and clinical significance of WFF after GSO implantation in paediatric patients.
Methods: Seventy-seven consecutive patients were enrolled. Periprocedural and
follow-up assessments included clinical,… More >
Open Access
ARTICLE
Han Zhang, Gang Li, Xiangming Fan, Junwu Su*
Congenital Heart Disease, Vol.15, No.5, pp. 361-367, 2020, DOI:10.32604/CHD.2020.013020
Abstract Background: To identify factors associated with shunt failure in
patients with a systemic pulmonary shunt (SPS). Methods: We retrospectively
assessed 451 patients who received SPS. Perioperative parameters such as hemoglobin, Nakata Index, and shunt size were assessed, and factors influencing shunt
failure after an initial palliative shunt operation were analyzed. Results: We analyzed 451 patients who underwent isolated SPS surgery at Anzhen Hospital. Of
these, shunt failure occurred in 48 (10.6%) cases after a median of 6.5 days. The
30-day mortality rate was 2.1%. Univariate and logistic regression analysis revealed
that a Nakata Index ≤ 105 and vasoactive-inotropic score (VIS)… More >
Open Access
ARTICLE
Sotiria C. Apostolopoulou1,*, Stella Brili2, Eftihia Sbarouni3, Dimitris Tousoulis2, Konstantinos Toutouzas2
Congenital Heart Disease, Vol.15, No.5, pp. 369-375, 2020, DOI:10.32604/CHD.2020.012092
Abstract Objective: Acquired coronary artery disease, initially thought to rarely
affect survivors of congenital heart disease, is increasingly recognized in this
population, as these patients grow in age and numbers in the recent era. This study
reports our experience with coronary artery disease in adults with congenital heart
disease and discusses treatment issues and the existing literature. Methods: Retrospective review of all charts of adults with congenital heart disease and acquired
coronary artery disease was performed. Patients’ clinical characteristics, diagnosis, risk factors, noninvasive and invasive imaging and management data were
recorded. Results: Coronary artery disease was diagnosed at 35–70 of age… More >
Open Access
ARTICLE
Mingjie Zhang1, Wenyi Luo1, Liping Wang1, Xi Chen1, Nan Bao2,*, Zhuoming Xu1,*
Congenital Heart Disease, Vol.15, No.5, pp. 377-386, 2020, DOI:10.32604/CHD.2020.011983
Abstract Background: This retrospective cohort study aimed to explore
the causes of death in children with congenital heart disease (CHD) after cardiac
surgery in one of the biggest cardiac centers for children with CHD in China.
Methods: A total of 26,856 children undergoing cardiac surgery from January
1, 2012 to December 31, 2019 were included. Based on the clinical data, the
causes of death were divided into ten categories and further compared among different periods, types of CHD and surgical procedures. Results: Of all patients,
513 (1.9%) died (median age 162 d, median weight 5.6 kg). The mortality in
2016–2019 was… More >
Open Access
ARTICLE
Jiachen Li, Xianchao Jiang, Sim-eng Zhang, Jinyang Liu, Yajuan Zhang, Jun Yan, Shoujun Li, Qiang Wang*
Congenital Heart Disease, Vol.15, No.5, pp. 387-397, 2020, DOI:10.32604/CHD.2020.013127
Abstract Background: Ebstein’s anomaly (EA) is a malformation of the tricuspid valve (TV) and myopathy of the right ventricle (RV). Surgery is now the main
treatment for the defect. Objective: To summarize our surgical results and experience based on patients with EA who were under 7 years of age and treated with
different surgical treatments. Design: Single-center cohort study of Ebstein’s
anomaly. Setting: China. Participants: 80 patients under 7 years old who were
diagnosed of EA and underwent different surgical treatments were consecutively
enrolled in our research from January 2010 to December 2019. Results: The median age of the 80 patients… More >