Vol.15, No.1, 2020-Table of Contents
  • Outcomes of Patients with Pulmonary Atresia with Intact Ventricular Septum Reaching Adulthood
  • Abstract Background: There is limited information on outcomes of adult patients with pulmonary atresia with intact ventricular septum (PA-IVS) due to the low incidence of disease and the large variation of surgical histories. Methods: Among 58 patients with repaired PA-IVS, a total of 32 patients aged ≥16 years and who were followed at our institution between January 2003 and December 2018 were reviewed. Surgical history, clinical outcomes, and laboratory, echocardiographic and electrocardiographic data were obtained by chart review. Results: Follow-up was from the age of 16 years and the median age at the latest follow-up was 23.7 years. Twenty-four patients had… More
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  • Cardiac Troponin Levels after Percutaneous Atrial Septal Defect Closure: A Qualitative Systematic Review and Meta-Analysis
  • Abstract Introduction: We conducted a systematic review and meta-analysis of published studies to determine the prevalence of troponin elevation after percutaneous atrial septal defect closure (pASDc) as well as to describe the association between troponin elevation and different anatomical risk factors for erosion. Methods: A qualitative systematic review and meta-analysis was undertaken. The selected studies included patients of any age receiving a pASDc; performed under transesophageal echocardiography monitoring; reporting troponin level measurement after the intervention; and indicating prevalence of troponin elevation and/or the association with risk factors for erosion. Results: Six studies were found which included 391 patients in total. The… More
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  • Transcatheter Closure of Coronary Artery Fistulae: A Literature Review
  • Abstract Coronary artery fistulae (CAFs) are anomalous connections that bypass the myocardial capillary bed between 1 or more coronary arteries and other cardiac chambers or other vessels. These fistulae are usually asymptomatic and are, thus, diagnosed incidentally. However, larger CAFs can cause various symptoms such as angina, exertional dyspnea, syncope, palpitation, and even sudden cardiac death. Treatment options include surgical closure and percutaneous transcatheter closure (TCC) with comparable safety and efficacy. The choice of device in TCC depends on the anatomic characteristics of the CAF, the age and size of the patient, the size of the occluded vessel, the appropriate size… More
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  • Preoperative Risk Assessment and Perioperative Management of Adults with Congenital Heart Disease Undergoing Non-Cardiac Surgery
  • Abstract Adults with congenital heart disease (ACHD) constitute a growing population with complex cardiac physiopathology and frequent extra-cardiac involvement. The recent dramatic improvement of their life expectancy has resulted in an increasing proportion of ACHD patients requiring non-cardiac surgery. While a large body of evidence demonstrated the importance of an accurate risk assessment in patients with acquired heart disease before noncardiac surgery in order to reduce perioperative morbidity and mortality and detailed algorithms have been released by international societies, no specific guidelines are available for the perioperative management in this population. Nonetheless, understanding the complex anatomy and unusual physiology of both… More
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  • QRS Duration and Outcome Late after Repair of Tetralogy of Fallot: Neurohormonal Activation Differentiates between Mechanical and Electrical Dyssynchrony
  • Abstract Background: Predicting the probability for sudden cardiac death (SCD) and thus evaluation of patients for electrical device therapy and/or ablation is one of the main tasks in clinics for adults with congenital heart disease (ACHD) following repaired tetralogy of Fallot (rTOF) patients. Previous data suggests that QRS complex analysis can help identifying those patients who subsequently suffer from SCD. We hypothesized that a long QRS duration is associated with adverse rhythm events if caused by conduction abnormalities but not if caused by right ventricular remodeling. Methods: A retrospective analysis was performed entailing all rTOF patients who were seen at our… More
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