Open Access

ARTICLE

Amitriptyline inhibits NLRP3 inflammasome activation via the ASM/CE pathway in a cell model of NAFLD

QIN LIU^1,#, CHUNYAN NIU^2,#,*, QIANG ZHANG³, SHIQIN SUN⁴, YUE CHEN², YONGQIANG SHI²

1 Shengli Clinical Medical College, Fujian Medical University, Fuzhou, 350001, China
2 Department of Gastroenterology, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing, 211200, China
3 Department of Gastroenterology, Yancheng Third People’s Hospital (The Yancheng School of Clinical Medicine of Nanjing Medical University), Yancheng, 224000, China
4 Administrative Department of Teaching and Scientific Research, Nanjing Lishui People’s Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing, 211200, China

* Corresponding Author: CHUNYAN NIU. Email:
# Contributed equally