Open Access

REVIEW

A perspective review on the biosynthesis of plant-based secondary metabolites and their application as potent drugs

JHILAM PRAMANIK^1,#, AKASH KUMAR², SARVESH RUSTAGI^3,#, MEHAK KATYAL⁴, SHEETAL THAKUR⁵, JUTISHNA BORA⁶, SUMIRA MALIK^6,7,*, ANCHAL TREHAN⁸, NAYAN TALUKDAR⁹, PETR SLAMA^10,*

1 Department of Food Technology, ITM University, Gwalior, India
2 Department of Food Technology, SRM University, Sonipat, India
3 Department of Food Technology, Uttaranchal University, Dehradun, India
4 Department of Nutrition and Dietetics, Manav Rachna International Institute of Research & Studies (MRIIRS), Faridabad, India
5 University Centre for Research and Development, UIBT, Chandigarh University, Mohali, India
6 Amity institute of Biotechnology, Amity University, Jharkhand, Ranchi, India
7 Department of Biotechnology, University Center for Research & Development (UCRD) Chandigarh University, Mohali, Punjab, India
8 Department of Science, Guru Nanak College of Pharmaceutical Sciences, Dehradun, India
9 Program of Biotechnology, Faculty of Science, Assam down town University, Guwahati, India
10 Department of Animal Morphology, Physiology and Genetics, Mendel University in Brno, Brno, Czech Republic

* Corresponding Authors: SUMIRA MALIK. Email: ; PETR SLAMA. Email:
# Represent equal contribution

BIOCELL 2024, 48(4), 541-557. https://doi.org/10.32604/biocell.2023.029031

Received 27 January 2023; Accepted 28 June 2023; Issue published 09 April 2024

Abstract

Many phytochemicals and their derived metabolites produced by plants are extensively employed in commercial goods, pharmaceutical products as well as in the environmental and medical fields. However, these secondary metabolites obtained from plants are in low amounts, and it is difficult to synthesize them at the industrial level. Despite these challenges, they may be utilized for a variety of medicinal products that are either available in the market or are being researched and tested. Secondary metabolites are complex compounds that exhibit chirality. Further, under controlled conditions with elicitors, desired secondary metabolites may be produced from plant cell cultures. This review emphasizes the various aspects of secondary metabolites including their types, synthesis, and applications as medicinal products. The article aims to promote the use of plant secondary metabolites in the management and treatment of various diseases.

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