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A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration

A. NOEL GRAVINA1,2, NOELIA D´ELÍA1,2, LUCIANO A. BENEDINI2,3,*, PAULA MESSINA1,2

1 Departamento de Química, Universidad Nacional del Sur (UNS), Bahía Blanca, 8000, Argentina
2 INQUISUR-CONICET, Universidad Nacional del Sur (UNS), Bahía Blanca, 8000, Argentina
3 Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS), Bahía Blanca, 8000, Argentina

* Corresponding Author: LUCIANO A. BENEDINI. Email: email

BIOCELL 2024, 48(11), 1517-1520. https://doi.org/10.32604/biocell.2024.055513

Abstract

This article navigates the relationship between biomaterials and osteogenic cell adhesion, highlighting the importance of mimicking the physiological response for bone tissue regeneration. Within this spirit is an initial description of the interaction between osteoblasts and osteoprogenitor cells with the extracellular matrix, explaining the leading role of integrins and cadherins in cell adhesion, and the intracellular signaling pathways elicited. Additionally, there is a focus on the strategies of advanced biomaterials that foster osteogenesis by replicating the native environment, taking advantage of these known specific signaling pathways. The final remarks lay on the need for careful consideration of in-vitro and in-vivo complexities in biomaterial development.

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APA Style
GRAVINA, A.N., D´ELÍA, N., BENEDINI, L.A., MESSINA, P. (2024). A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration. BIOCELL, 48(11), 1517-1520. https://doi.org/10.32604/biocell.2024.055513
Vancouver Style
GRAVINA AN, D´ELÍA N, BENEDINI LA, MESSINA P. A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration. BIOCELL . 2024;48(11):1517-1520 https://doi.org/10.32604/biocell.2024.055513
IEEE Style
A.N. GRAVINA, N. D´ELÍA, L.A. BENEDINI, and P. MESSINA, “A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration,” BIOCELL , vol. 48, no. 11, pp. 1517-1520, 2024. https://doi.org/10.32604/biocell.2024.055513



cc Copyright © 2024 The Author(s). Published by Tech Science Press.
This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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