Open Access

ARTICLE

Fang-Xia-Dihuang decoction inhibits breast cancer progression induced by psychological stress via down-regulation of PI3K/AKT and JAK2/STAT3 pathways: An in vivo and a network pharmacology assessment

LINGYAN LV^1,2,#, JING ZHAO^1,2,#, XUAN WANG^1,2, LIUYAN XU^1,2, YINGYI FAN², CHUNHUI WANG³, HONGQIAO FAN^4,5,*, XIAOHUA PEI^5,*

1 School of Graduate, Beijing University of Chinese Medicine, Beijing, 100029, China
2 Department of Breast, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, 100029, China
3 Department of Pharmacy, Fangshan Hospital of Beijing University of Chinese Medicine, Beijing, 102488, China
4 Department of Breast, The First Hospital of Hunan University of Chinese Medicine, Changsha, 410007, China
5 Department of Chest and Breast, The Xiamen Hospital of Beijing Universality of Chinese Medicine, Xiamen, 361001, China

* Corresponding Authors: HONGQIAO FAN. Email: ; XIAOHUA PEI. Email:
# Lingyan Lv and Jing Zhao contributed equally to this work