Open Access
REVIEW
Mannose metabolism and immune regulation: Insights into its therapeutic potential in immunology-related diseases
School of Life Sciences, Changchun Normal University, Changchun, 130032, China
* Corresponding Author: KAI SONG. Email:
BIOCELL 2023, 47(11), 2535-2546. https://doi.org/10.32604/biocell.2023.030781
Received 31 July 2023; Accepted 14 September 2023; Issue published 27 November 2023
Abstract
Mannose, a different isomer of the hydroxyl group at the C-2 position of glucose, shares the same transport carrier protein with glucose to enter cells and participate in the regulation of glucose metabolism. It affects cell growth, differentiation, and function and plays an active role in tumor immunity and inflammatory processes. This paper provides theoretical support for expanding the clinical applications of mannose by exploring its constitution, metabolic pathways, and role in regulating immune cell function and treating immunology-related diseases.Graphic Abstract
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