Open Access
VIEWPOINT
Cardiac stromal cells on stage: From dull filler to specialized actors
VITTORIO PICCHIO1, FRANCESCA PAGANO2, ISOTTA CHIMENTI1,3,*
1 Department of Medical Surgical Sciences and Biotechnologies, Sapienza University, Latina, 04100, Italy
2 Institute of Biochemistry and Cell Biology, National Council of Research (IBBC-CNR), Monterotondo, 00015, Italy
3 Mediterranea Cardiocentro, Napoli, 80122, Italy
* Corresponding Author: Isotta Chimenti,
BIOCELL 2022, 46(8), 1875-1877. https://doi.org/10.32604/biocell.2022.020181
Received 09 November 2021; Accepted 13 December 2021; Issue published 22 April 2022
Abstract
Cardiac stromal cells have faced through the years a significant evolution in their definitions concerning their
phenotypes, markers, and functions. They are surging to key roles in physiopathology, becoming important targets to be
exploited for cardiac repair. In this perspective, we briefly discuss their role in novel therapeutic strategies for enhancing
cardiac repair and regeneration.
Keywords
Cite This Article
PICCHIO, V., PAGANO, F., CHIMENTI, I. (2022). Cardiac stromal cells on stage: From dull filler to specialized actors.
BIOCELL, 46(8), 1875–1877. https://doi.org/10.32604/biocell.2022.020181