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ARTICLE

Ex vivo cartilage explant model for the evaluation of chondrocyte-targeted exosomes

KAN OUYANG^1,2,#, MEIQUAN XU^3,#, YUJIE LIANG⁴, XIAO XU², LIMEI XU², CAINING WEN^1,2, ZHUAN QIN², YIXIN XIE², HUAWEI ZHANG⁵, LI DUAN^2,*, DAPING WANG^1,2,5,*

1 Guangzhou Medical University, Guangzhou, 510095, China
2 Department of Sports Medicine, Guangdong Provincial Research Center for Artificial Intelligence and Digital Orthopedic Technology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital, Shenzhen, 518035, China
3 Deparment of Pathology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People’s Hospital, Shenzhen, 518035, China
4 Shenzhen Key Laboratory for Psychological Healthcare, Shenzhen Institute of Mental Health, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen, 518020, China
5 Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, 518055, China

* Address correspondence to: Li Duan, ; Daping Wang,
# These authors contributed equally to this work