Open Access

VIEWPOINT

Periodontal research contributions to basic sciences: From cell communication and host-parasite interactions to inflammation and bone biology

by RAFAEL SCAF DE MOLON^1,2,*, ERICA DORIGATTI DE AVILA², JONI AUGUSTO CIRELLI², JOAO PAULO STEFFENS³

1 Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, 21941-617, Brazil
2 São Paulo State University - UNESP, Araraquara, 14801-930, Brazil
3 Federal University of Parana - UFPR, Curitiba, 80210-170, Brazil

* Corresponding Author: RAFAEL SCAF DE MOLON. Email:

BIOCELL 2022, 46(3), 633-638. https://doi.org/10.32604/biocell.2022.018031

Received 02 June 2021; Accepted 13 August 2021; Issue published 18 November 2021

Abstract

The periodontium comprises all structures surrounding the teeth, including gingiva, root cementum, periodontal ligament and alveolar bone. Those tissues aim to protect and support the teeth and are challenged by a residing microbiota that leads to subclinical inflammation even in physiological conditions. Periodontitis, a prevalent multicausal inflammatory and destructive disease, develops as a result from complex host-parasite interactions. This unique physiologic and pathologic scenario enables the development of research methods which allows conclusions beyond the simple understanding of periodontal homeostasis. The aim of this viewpoint was to explore potential contributions of periodontal research to a wide array of basic science specialties, such as cell and molecular biology, microbiology, immunology, endocrinology, rheumatology, among others.

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