Open Access iconOpen Access

VIEWPOINT

Ready to migrate? Reading cellular signs of migration in an epithelial to mesenchymal transition model

TAMARA FERNÁNDEZ-CALERO1,2,3,#, IGNACIO LÓPEZ1,#, MARCOS DAVYT1, CORA CHALAR1, RICARDO EHRLICH1,4, MÓNICA MARÍN1,*

1 Biochemistry-Molecular Biology, Faculty of Science, Universidad de la República, Montevideo, 11400, Uruguay
2 Bioinformatics Unit, Institut Pasteur de Montevideo, Montevideo, 11400, Uruguay
3 Departamento de Ciencias Exactas y Naturales, Universidad Católica del Uruguay, Montevideo, 11600, Uruguay
4 Institut Pasteur de Montevideo, Montevideo, 11400, Uruguay

* Corresponding Author: MÓNICA MARÍN. Email: email

(This article belongs to the Special Issue: Tumor Microenvironment and Cytoskeletal Dynamics)

BIOCELL 2022, 46(11), 2353-2356. https://doi.org/10.32604/biocell.2022.020966

Abstract

The epithelial to mesenchymal transition (EMT) is a cellular program that drives de-differentiation of cells in both physiological and pathological processes. One of the characteristics of cells describing an EMT is the (re)acquisition of a motility capacity that allows them to migrate through the original tissue as well as to other sites in the organism. The molecular mechanisms that control the EMT are rapidly emerging and here we add to the idea that the adaptation required for cells to commit to the EMT includes adjustments of the translation machinery and metabolic pathways to cope with a high demand of extracellular components.

Keywords


Cite This Article

APA Style
FERNÁNDEZ-CALERO, T., LÓPEZ, I., DAVYT, M., CHALAR, C., EHRLICH, R. et al. (2022). Ready to migrate? reading cellular signs of migration in an epithelial to mesenchymal transition model. BIOCELL, 46(11), 2353-2356. https://doi.org/10.32604/biocell.2022.020966
Vancouver Style
FERNÁNDEZ-CALERO T, LÓPEZ I, DAVYT M, CHALAR C, EHRLICH R, MARÍN M. Ready to migrate? reading cellular signs of migration in an epithelial to mesenchymal transition model. BIOCELL . 2022;46(11):2353-2356 https://doi.org/10.32604/biocell.2022.020966
IEEE Style
T. FERNÁNDEZ-CALERO, I. LÓPEZ, M. DAVYT, C. CHALAR, R. EHRLICH, and M. MARÍN, “Ready to migrate? Reading cellular signs of migration in an epithelial to mesenchymal transition model,” BIOCELL , vol. 46, no. 11, pp. 2353-2356, 2022. https://doi.org/10.32604/biocell.2022.020966



cc Copyright © 2022 The Author(s). Published by Tech Science Press.
This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
  • 1214

    View

  • 530

    Download

  • 0

    Like

Share Link