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Single-cell systems neuroscience: A growing frontier in mental illness

SEAN J. O’SULLIVAN^1,2,*

1 Daniel Baugh Institute for Functional Genomics and Computational Biology, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, USA
2 Brain Stimulation Laboratory, Stanford University, Stanford, USA

* Corresponding Author: SEAN J. O’SULLIVAN. Email:

BIOCELL 2022, 46(1), 7-11. https://doi.org/10.32604/biocell.2022.017680

Received 30 May 2021; Accepted 19 July 2021; Issue published 28 September 2021

Abstract

The development of effective treatments for psychiatric disease has been disappointing in recent decades given the advancements in neuroscience. Moreover, rising rates of mental illness such as addiction and depression compel scientists and physicians to discover novel and creative solutions. One such approach that has proven effective is systems neuroscience: A focus on networks as opposed to mechanism. Further, investigation at the single-cell and circuit level is likely to be fruitful in such endeavors as this resolution describes the functional psychopathology that allows for intervention.

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