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REVIEW

Advances in molecular regulation of goat lipid metabolism and FAS structure and function regulation

JIAHE GUO^2,#, XIAOGUANG JI^3,#, YONGJIANG MAO², ZHANGPING YANG², ZHI CHEN², YUAN YUAN^1,*

1 School of Nursing, Yangzhou University, Yangzhou, 225009, China.
2 College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China.
3 Hubei Blue Valley Microbial Technology Co., Ltd., Yichang, 443100, China

* Corresponding Author:Yuan Yuan,
# These authors contributed equally to this work.

(This article belongs to the Special Issue: Decoding Gene (including circRNA, lincRNA miRNA and mRNA) Expression)

BIOCELL 2021, 45(4), 835-847. https://doi.org/10.32604/biocell.2021.015652

Received 02 January 2021; Accepted 24 February 2021; Issue published 22 April 2021

Abstract

Goat milk is widely recognized for its nutritional value. Fatty acid synthase (FAS) is the crucial enzyme of fatty acid de novo synthesis. It plays an important role in the formation of goat milk fat. In this paper, we first introduced the molecular regulation process of goat milk fat metabolism based on the structure research of FAS. Secondly, we reviewed some key factors in FAS transcription and post-transcriptional regulation of the goat mammary gland and preliminarily constructed the expression network of the goat mammary gland FAS gene. The purpose of this paper is to systematically introduce the role of FAS in goat milk fat metabolism and to provide a reference for future studies on the mechanism of goat milk fat metabolism.

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