Vol.45, No.3, 2021, pp.451-459, doi:10.32604/biocell.2021.014289
OPEN ACCESS
REVIEW
Anti-nutritional characteristics and mechanism of soybean agglutinin
  • LI PAN1, JIAWEI LIU1, MOHAMMED HAMDY FAROUK2,*, GUIXIN QIN1,*, NAN BAO1, YUAN ZHAO1, HUI SUN1
1 Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Key Laboratory of Animal Nutrition and Feed Science, College of Animal Science and Technology, Jilin Agricultural University, Changchun, 130118, China
2 Animal Production Department, Faculty of Agriculture, Al-Azhar University, Cairo, 11884, Egypt
* Corresponding Author: Mohammed Hamdy Farouk. Email: ; Guixin Qin. Email:
Received 15 September 2020; Accepted 21 December 2020; Issue published 03 March 2021
Abstract
Soybean agglutinin (SBA) is an important anti-nutritional factor in soybean. SBA can induce animal growth inhibition, cause pathological changes of intestinal tissue, and decrease in the immune system functioning. Recently, a great deal of research has been done on the effects of SBA on cell morphology, division, apoptosis, autophagy, as well as the correlated signal transduction pathway. This review mainly covers the chemical and biological characteristics of SBA, describes the multifaceted aspects of SBA anti-nutritional functions, and highlights the possible cellular and molecular mechanism of anti-nutritional effects of SBA. This review has important implications for the prevention and treatment of SBA-induced diseases, drug development, processing techniques of plant products, prevention of food- borne toxins, as well as human and animal health protection.
Keywords
Soybean agglutinin; Autophagy; Cell apoptosis; Anti-nutritional functions; Cell signaling
Cite This Article
PAN, L., LIU, J., FAROUK, M. H., QIN, G., BAO, N. et al. (2021). Anti-nutritional characteristics and mechanism of soybean agglutinin. BIOCELL, 45(3), 451–459.
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