Open Access

REVIEW

COVID-19: Review on Its Etiology, Pathogenesis, and Existence in Humans

VIVEK KUMAR, VISHNU AGARWAL^*

Department of Biotechnology, Motilal Nehru National Institute of Technology, Allahabad, 211004, India

* Address correspondence to: Vishnu Agarwal,

BIOCELL 2020, 44(4), 461-467. https://doi.org/10.32604/biocell.2020.011090

Received 19 April 2020; Accepted 18 August 2020; Issue published 24 December 2020

Abstract

The world is facing a new healthcare crisis with the rise and spread of novel coronavirus since December 2019. Also known as Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2), the disease associated with SARSCoV-2 is even called COVID-19. The infection is said to have originated from the bat community and transmitted to humans through an intermediate host (yet unknown) in Wuhan, in the Hubei region of China. COVID-19 is having a pulverizing impact on the scientific community. As of August 13, 2020, the number of confirmed cases had reached up to 20,439,814 and the death toll to 744,385, affecting more than 188 territories across the globe. In these difficult times, the world is looking towards research and clinical work from different scientific communities to lead the way to a solution to the issue. In this review, we are focusing on COVID-19 emergence, pathogenicity, and existence in humans, as well as the SARS-CoV-2 infection mechanism and its similarities to previous coronavirus strains.

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Keywords

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