Open Access

ARTICLE

Leptin promotes proliferation and invasion of osteosarcoma cells by upregulating the expression of SIRT1

HELIN FENG^1,2, XIAOCHONG ZHANG³, QIANQIAN ZHANG⁴, ZE LI⁵, LILI ZHAO^1,6,*

1 Xingtai People’s Hospital Postdoctoral Workstation, Hebei Province Xingtai People’s Hospital, Xingtai, 054031, China
2 Department of Orthopedics, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050011, China
3 Department of Research and Education, Hebei Province Xingtai People’s Hospital, Xingtai, 054031, China
4 Department of Gynecology, Hebei Medical University Second Affiliated Hospital, Shijiazhuang, 050000, China
5 Department of Emergency, Hebei Medical University Second Affiliated Hospital, Shijiazhuang, 050000, China
6 Department of Orthopedics, Xingtai People’s Hospital, Xingtai, 054031, China

* Address correspondence to: Lili Zhao,