Open Access

REVIEW

Current status of gene therapy in melanoma treatment

YONGLU WANG^1,2,*, WEI YOU¹, XUEMING LI^3,4,*

1 College of Pharmacy, Nanjing Tech University, Nanjing, China
2 College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
3 Nanjing Bestform Pharmaceutical Technology Co., Ltd., Nanjing, China
4 Postgraduate Department, Nanjing Tech University, Nanjing, China

* Address correspondence to: Yonglu Wang, ; Xueming Li,

BIOCELL 2020, 44(2), 167-174. https://doi.org/10.32604/biocell.2020.09023

Received 04 November 2019; Accepted 16 April 2020; Issue published 27 May 2020

Abstract

Melanoma is the deadliest type of skin cancer and which has a high ability of metastasis. Surgery is an effective method to treat I or II stage melanoma patients. However, there are few treatment options for metastatic melanoma. Gene therapy is one of the attractive options and is considered as the future direction for treating melanoma. This review mainly discusses the properties and challenges of the various gene therapies in melanoma, especially the delivery systems and gene targeting.

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Citations