Open Access
REVIEW
Coxiella burnetii: living inside the host cell
Jesus Sebastian DISTEL1, Walter BERON1, Rodolfo Matias ORTIZ FLORES1,2
1
Instituto de Histología y Embriología de Mendoza (IHEM), CONICET, Universidad Nacional de Cuyo, Mendoza, Argentina
2
Facultad de Odontología, Universidad Nacional de Cuyo, Mendoza, Argentina
Address correspondence to: Rodolfo Matias Ortiz Flores,
BIOCELL 2019, 43(1), 1-6. https://doi.org/10.32604/biocell.2019.07021
Abstract
Coxiella burnetii is an obligate intracellular pathogen and the causative agent of Q fever. In this brief review, we describe how recently described mechanisms help our understanding of
C. burnetii invasion and its survival in the host cell by the formation of a replicative niche: the
Coxiella-containing vacuole. We describe the actin-associated proteins involved in the internalization of
C. burnetii, and we discuss the contribution of diverse degradation pathways of the cell during the formation and stabilization of the
Coxiella-containing vacuole.
Keywords
Cite This Article
APA Style
DISTEL, J.S., BERON, W., FLORES, R.M.O. (2019). coxiella burnetii: living inside the host cell. BIOCELL, 43(1), 1-6. https://doi.org/10.32604/biocell.2019.07021
Vancouver Style
DISTEL JS, BERON W, FLORES RMO. coxiella burnetii: living inside the host cell. BIOCELL . 2019;43(1):1-6 https://doi.org/10.32604/biocell.2019.07021
IEEE Style
J.S. DISTEL, W. BERON, and R.M.O. FLORES "Coxiella burnetii: living inside the host cell," BIOCELL , vol. 43, no. 1, pp. 1-6. 2019. https://doi.org/10.32604/biocell.2019.07021