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REVIEW

Coxiella burnetii: living inside the host cell

by Jesus Sebastian DISTEL, Walter BERON, Rodolfo Matias ORTIZ FLORES

1 Instituto de Histología y Embriología de Mendoza (IHEM), CONICET, Universidad Nacional de Cuyo, Mendoza, Argentina
2 Facultad de Odontología, Universidad Nacional de Cuyo, Mendoza, Argentina

Address correspondence to: Rodolfo Matias Ortiz Flores, email

BIOCELL 2019, 43(1), 1-6. https://doi.org/10.32604/biocell.2019.07021

Abstract

Coxiella burnetii is an obligate intracellular pathogen and the causative agent of Q fever. In this brief review, we describe how recently described mechanisms help our understanding of C. burnetii invasion and its survival in the host cell by the formation of a replicative niche: the Coxiella-containing vacuole. We describe the actin-associated proteins involved in the internalization of C. burnetii, and we discuss the contribution of diverse degradation pathways of the cell during the formation and stabilization of the Coxiella-containing vacuole.

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APA Style
Sebastian DISTEL, J., BERON, W., Matias ORTIZ FLORES, R. (2019). coxiella burnetii: living inside the host cell. BIOCELL, 43(1), 1-6. https://doi.org/10.32604/biocell.2019.07021
Vancouver Style
Sebastian DISTEL J, BERON W, Matias ORTIZ FLORES R. coxiella burnetii: living inside the host cell. BIOCELL . 2019;43(1):1-6 https://doi.org/10.32604/biocell.2019.07021
IEEE Style
J. Sebastian DISTEL, W. BERON, and R. Matias ORTIZ FLORES, “Coxiella burnetii: living inside the host cell,” BIOCELL , vol. 43, no. 1, pp. 1-6, 2019. https://doi.org/10.32604/biocell.2019.07021



cc Copyright © 2019 The Author(s). Published by Tech Science Press.
This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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