Open Access

ARTICLE

Spontaneous running wheel improves neuroprotection efficacy of ischemic postconditioning in mice following ischemia/reperfusion injury

Hong YE^1,6,#, WeiWei Wang^2,#, Yu Ding^3,#, XiaoLei Liu^4,#, WenJI Jia¹, WeiLi Luo¹, HuiJuan Fan¹, HongQun Zhou¹, Jin Wang¹, JianLong Ju¹, DongMing Zhou⁷, TianHao Bao^5,1,*, YuHong Zhu^1,*

1 Department of Neurology, the Second Affiliated Hospital of Kunming Medical University, Kunming, China
2 Department of Cardiology, the Second Affiliated Hospital of Kunming Medical University, Kunming, China
3 Department of Ultrasound, the Second Affiliated Hospital of Kunming Medical University, Kunming, China
4 Department of Neurology, the First Affiliated Hospital of Kunming Medical University, Kunming, China
5 The Mental Health Center of Kunming Medical University, Kunming, China
6 Kunming Medical University, Kunming, China
7 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada
# Hong Ye, Yu Ding, WeiWei Wang, XiaoLei Liu contributed equally to this article.

^* Address correspondence to: TianHao Bao, ; YuHong Zhu,