Guest Editors
Dr. Gozde Eke
Email: gozdeeke@gmail.com
Affiliation: Laboratoire d'Analyse et d'Architecture des Systmes, Centre National de la Recherche Scientifique (LAAS-CNRS), Universit de Toulouse, INSA, UPS, 31400 Toulouse, France
Homepage:
Research Interests: angiogenesis, neo-vascularization, tissue regeneration, biomaterials, tissue engineering, 3D printing, bioprinting, microenvironment, spheroids, organ on a chip, stem cells
Summary
This special issue aims to explore the intricate cellular and molecular mechanisms underlying tissue regeneration, vascularization, and the construction of functional organoids. It will focus on the dynamic interplay between stem cells, tissue microenvironments, and bioengineered materials that drive the formation and regeneration of complex tissue structures. Special emphasis will be placed on how cellular behavior is regulated in the context of angiogenesis, neovascularization, for development of functional organoids. We will also highlight the cutting-edge use of nanotechnology in enhancing tissue regeneration.
The following key research areas will be covered but not limited to:
1. Stem Cells in Tissue Regeneration:
Investigating all types of stem cells in tissue repair and regeneration. This includes exploring the molecular mechanisms through which stem cells respond to different biomaterials to promote tissue formation, vascularization, and functional recovery.
2. Angiogenesis and Microenvironment Regulation:
Delving into the molecular pathways and signaling networks involved in angiogenesis, with a particular focus on the role of growth factors and engineered biomaterials in promoting vascular growth. The issue will highlight how modifying the cellular microenvironment can enhance vascularization during tissue regeneration.
3. Microengineering and Organoid Construction:
Exploring the use of microengineering technologies and 3D bioprinting in creating functional organoids, particularly those with vascular networks. Research on the development of organoid models as platforms for disease modeling, drug screening, and regenerative medicine applications will be discussed.
4. Cell-Microenvironment Interactions:
Investigating how cells perceive and respond to their surrounding microenvironment, particularly focusing on the mechanistic role of physical and chemical cues in guiding cellular behavior during tissue regeneration, wound healing, and cancer progression.
Keywords
tissue regeneration, vascularization, stem cells, spheroids, organoids, angiogenesis, bioengineering, 3D printing, bioprinting, biomaterials, microenvironment
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