Guest Editors
Dr. Hans-Uwe Dahms, Kaohsiung Medical University, hudahms11@gmail.com
Dr. Mei-fang CHO, Southern Taiwan University of Technology and Science, mfcce@stust.edu.tw
Summary
Biomarkers are measurable indicators of biological conditions at different levels of integration. Biomarkers in OMICs studies are used and evaluated to study normal biological processes, pathological processes, or pharmacological responses to a therapeutic intervention.
This special issue is focusing on the challenges toxicology is faced with in terms of regulation, effect, and mechanisms of action related to interactions of compounds, cells, organisms, and human individual and public health.
We welcome molecular biologists, chemists, physicists, and medical researchers to contribute original experimental or theoretical research articles and reviews on related topics.
Keywords
Toxicology, Pharmacology, Biomarker, Bioassay, Bioindication, Biomedicine, Physiology, Bioinformatics, Chemcomputation, Modeling
Published Papers
-
Open Access
REVIEW
The Potential Toxic Side Effects of Flavonoids
ZHIMEI TANG, QIANG ZHANG
BIOCELL, Vol.46, No.2, pp. 357-366, 2022, DOI:10.32604/biocell.2022.015958
（This article belongs to this Special Issue:
Biomonitoring of Toxic Effects Using OMICs Markers)
Abstract Flavonoids are a class of phytochemical molecules abundant in many plants, fruits, vegetables, and leaves.
Flavonoids possess a series of significant biological activities, including anticancer, antioxidant, antiviral, and antiinflammatory properties. They become an important source of dietary supplements and natural health products.
Though many studies confirmed the safety of flavonoids, the potential toxicity of flavonoids is still a remarkable field
of research to be explored. The enthusiasm for flavonoids expressed by the public has sometimes overlooked their
toxicity and also consumed the flavonoids exceeding the body requirements. The current review focused on the
potential toxicity of flavonoids to make the…
More >
-
Open Access
REVIEW
Carbon nanotubes: A review on risks assessment, mechanism of toxicity and future directives to prevent health implication
PIYOOSH KUMAR BABELE, MAHENDRA KUMAR VERMA, RAVI KANT BHATIA
BIOCELL, Vol.45, No.2, pp. 267-279, 2021, DOI:10.32604/biocell.2021.013409
（This article belongs to this Special Issue:
Biomonitoring of Toxic Effects Using OMICs Markers)
Abstract Carbon nanotubes (CNTs) have tremendous applications in almost every walk of life; however, their harmful
impacts on humans and the environment are not well addressed. CNTs have been used in various applications ranging
from medical science to different engineering branches, to ease human life. Generally, the toxicological profile of CNTs
under laboratory conditions cannot be assessed primarily in medical science due to the inconsistent availability of
cytotoxic study data. CNT toxicity has been affected by many physicochemical properties (e.g., size, type of
functionalization), concentration, the extent of exposure, mode of exposure, and even the solvents/medium used to
dissolve/disperse CNTs for…
More >
-
Open Access
ARTICLE
In silico assessment of human health risks caused by cyanotoxins from cyanobacteria
JIA-FONG HONG, BAGHDAD OUDDANE, JIANG-SHIOU HWANG, HANS-UWE DAHMS
BIOCELL, Vol.45, No.1, pp. 65-77, 2021, DOI:10.32604/biocell.2021.014154
（This article belongs to this Special Issue:
Biomonitoring of Toxic Effects Using OMICs Markers)
Abstract Harmful algal blooms (HABs) that are formed by cyanobacteria have become a serious issue worldwide in
recent years. Cyanobacteria can release a type of secondary metabolites called cyanotoxins into aquatic systems which
may indirectly or directly provide health risks to the environment and humans. Cyanotoxins provide some of the
most powerful natural poisons including potent neurotoxins, hepatotoxins, cytotoxins, and endotoxins that may result
in environmental health risks, and long-term morbidity and mortality to animals and humans. In this research, we
used the chemcomputational tool Molinspiration for molecular property predictions, Pred-hERG 4.2 web software for
cardiac toxicity prediction, and Pred-Skin 2.0…
More >
Login
Register
Submit a Paper
Propose a Special lssue