Guest Editors
Prof. Lei Yang,
Department of Orthopedics, Nanjing Medical University, Nanjing, China
leiyang@njmu.edu.cn
Prof. Athanasios E. Athanasiou,
Department of Medical Oncology, Metaxa Cancer Hospital, Botassi 51, 18537, Piraeus, Greece
editorial_office@jbuon.com
Prof. Francesco Busardò,
University Politecnica delle Marche, Ancona, Italy
f.busardo@univpm.it
Summary
Non-Coding RNAs (ncRNAs) are RNA molecules transcribed from the genome that do not encode proteins, and can be divided into small noncoding RNAs (snRNAs, snoRNAs, miRNAs, and piRNAs) and long noncoding RNAs (>200 nucleotides). More and more evidence have demonstrated the important role of ncRNAs in the physiological and pathological processes of human cancers. Due to the wide variety of ncRNAs and their mechanisms of action, it is a difficult task to understand how changes in ncRNA expression promote the progression of cancer. In addition, changes in ncRNA expression levels are usually cancer-specific or even subtype-specific, which makes the wide application of research results challenging. Nevertheless, an in-depth understanding of the nuances of ncRNA regulation provides more opportunities for new therapeutic targets. The main aim of this special issue is to further understand the mechanism of ncRNAs and their influences on the signaling network of cancers in order to develop better prognosis and treatment strategies.
This special issue on the “Non-Coding RNAs in the Regulation of Human Cancers” welcomes interesting articles as well as reviews that focus on the emerging important role of non-coding RNAs in the diagnosis and treatment of kinds of cancers.
Areas of interest include, but are not limited to:
1) The molecular mechanism of miRNAs in the occurrence and development of human cancers;
2) The molecular mechanism of lncRNAs in the occurrence and development of human cancers;
3) The molecular mechanism of circRNAs in the occurrence and development of human cancers;
4) The molecular mechanism of snRNAs in the occurrence and development of human cancers;
5) The molecular mechanism of , snoRNAs in the occurrence and development of human cancers;
6) The molecular mechanism of , piRNAs in the occurrence and development of human cancers;
7) Biological functions of ncRNAs combined with exosomes in human cancers;
8) Bioinformatics of ncRNAs in human Cancers;
9) Systematic review and Meta-analysis of ncRNAs in human Cancers;
10) The role of ncRNAs in the therapeutic effects and prognosis of human Cancers.
Keywords
Non-Coding RNAs, Diagnosis, Cancer, Biomarker, Therapeutics
Published Papers
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