Guest Editors
Prof. Dr. Shoib Ahmad Baba
Affiliation: Department of Education, Government of Jammu and Kashmir
CSIR-Indian Institute of Integrative Medicine, Jammu, India
Email: shoaibnazir25@gmail.com
Dr. Arpita Roy
Affiliation: Department of Biotechnology, School of Engineering & Technology, Sharda University, Greater Noida, India
Email: arpita.roy@sharda.ac.in
Summary
Chronic inflammation can result in the development of wide array of diseases such as cancer, obesity, asthma, rheumatoid arthritis, and heart diseases to name a few. Although a large number of research efforts have been put in to prevent and treat inflammation-related diseases, the overall incidence is still increasing, and the scenario is becoming worst day by day. Additionally, the mechanism underlying these diseases is still largely unknown.
Inflammation being one of the prevalent feature of many diseases, results in dysfunction/dysregulation of specific cells and tissues leading to development of the disease. Consequently, a wide array of studies have been directed to investigate the mechanism of chronic inflammation in the in vitro and in vivo systems to develop drugs to overcome inflammation mediated diseases. Natural products and their constituents have been used widely used for the management of several inflammation related diseases such as cancer from ancient times. Several related studies have deciphered biological mechanisms of action of natural products which have been translated into clinical practice of herbal extracts and natural products. Furthermore, research in this direction will help to enhance the availability of therapeutic strategies based on natural products for the management of inflammation related diseases.
The aim of this Special Issue is to publish high-quality original research and review papers evaluating the potential of natural products in complementary and alternative medicine (CAM) for the management of inflammation related diseases. Emerging approaches to evaluate pharmacology, toxicology, and mechanism of action of natural products are also welcome.
Potential topics include but are not limited to the following:
· Evaluation of protective effects of natural products in vitro and in vivo models of inflammation-related diseases
· Underling mechanism of action of natural products in inflammation-related diseases
· Network pharmacology to identify targets of natural products
· Effect of natural products on chronic inflammation-related signalling cascades
· Phytochemical analysis of natural products used for inflammation-related diseases
· Studying interactions of natural products in animal models of chronic inflammatory diseases
· Effects of natural products on regulatory RNAs involved in chronic inflammatory diseases.
· Toxicology of natural products used against chronic inflammatory diseases
Keywords
Natural products, Inflammation, Network pharmacology, Regulatory RNAs, Toxicology, Molecular targets, diseases
Published Papers
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