Guest Editors
Peng Xiao, Zhejiang University, China, tulipxp@zju.edu.cn
Yinjing Song, Zhejiang University, China, 11218067@zju.edu.cn
Lu Sun, University of Michigan (Current), USA, lusun@umich.edu
Summary
The immunosuppressive microenvironment present in tumor tissues presents significant challenges to effective anti-tumor immunity and cancer immunotherapy. Dysfunctions in immune cells, including macrophages, T cells, neutrophils, and dendritic cells, play a major role in facilitating tumor immune evasion. Addressing the reversal of the immunosuppressive properties exhibited by tumor-infiltrating immune cells has remained a top priority in cancer treatment. Furthermore, the identification of key molecules that regulate immune cell functions within the tumor microenvironment, along with a comprehensive understanding of their mechanisms of action, may offer new targets for cancer immunotherapy.
The objective of this special issue is to advance our current understanding of the regulatory mechanisms governing immune cell functions in cancer. We invite original research articles and reviews that explore the following areas:
(1) Discovery of novel immune cell populations or molecules that influence anti-tumor immunity.
(2) Elucidation of the molecular mechanisms underlying the regulatory roles of immune cells in cancer progression.
(3) Targeting immune cells in cancer immunotherapy.
(4) Identification of new biomarkers associated with immune cells that can predict patients' response to immunotherapy.
Please note that we do not accept studies solely comprising bioinformatics analysis of public databases without any validation data.
Keywords
cancer, immune cells, cancer immunotherapy, tumor microenvironment
Published Papers
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