Guest Editors
Prof. Dr. Kyung-Wan Baek
Email: baekbo1218@gmail.com
Affiliation: Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea; Department of Physical Education, Gyeongsang National University, Jinju 52828, Republic of Korea
Homepage:
Research Interests: exercise, immune, aging, metabolic syndrome, genomics, genetics, molecular biology
Prof. Dr. Jeong-An Gim
Email: vitastar@sch.ac.kr
Affiliation: Medical Science Research Center, College of Medicine, Korea University Guro Hospital, Seoul, 08308, Republic of Korea
Homepage:
Research Interests: bioinformatics, epigenetics, aging, genomics, health management
Summary
Exercise has profound effects on cellular and molecular processes, influencing various biological systems such as the gut microbiome, immune function, and metabolic health. This special issue aims to explore the underlying mechanisms through which exercise modulates these systems, particularly in the context of aging, chronic diseases like chronic kidney disease (CKD), and metabolic disorders such as obesity.
By compiling innovative research from global experts, this issue seeks to unravel the complex interplay between exercise and its molecular effects on health and disease. Key areas of focus include but are not limited to:
1. Exercise and the Gut Microbiome:
-Investigating how physical activity modulates gut microbiota composition and function.
-Exploring the cellular pathways through which exercise-induced changes in the microbiome impact systemic health, metabolism, and immune responses.
2. Exercise and Chronic Kidney Disease (CKD):
-Examining how exercise affects cellular signaling and protective mechanisms in CKD.
-Understanding the molecular pathways by which exercise may slow CKD progression and improve kidney function.
3. Exercise and Immunosenescence:
-Analyzing how regular physical activity mitigates the aging of the immune system.
-Exploring the role of exercise in reversing immune system decline through modulation of key immune cells and cytokine signaling pathways.
4. Exercise and Obesity:
-Unveiling the molecular mechanisms by which exercise combats obesity and metabolic dysfunction.
-Studying how exercise regulates lipid metabolism, insulin sensitivity, and inflammation at the cellular level.
5. Exercise-Induced Cellular Adaptations:
-Identifying key molecular signals and cellular adaptations triggered by exercise, including stress response pathways and mitochondrial function.
-Investigating the long-term benefits of exercise on cellular health and tissue regeneration in chronic diseases.
Through this special issue, we aim to foster interdisciplinary collaboration and enhance our understanding of how exercise exerts its beneficial effects at the cellular and molecular levels. We welcome original research articles, comprehensive reviews, and perspectives that delve into the multifaceted roles of exercise in promoting health and mitigating disease through molecular mechanisms.
By highlighting the latest discoveries and challenges in the field, this issue strives to pave the way for novel therapeutic strategies and exercise-based interventions in aging, chronic disease, and metabolic health.
Keywords
exercise, gut microbiome, chronic kidney disease, immunosenescence, obesity, metabolic health, molecular mechanisms, cellular adaptations, chronic disease
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