Guest Editors
Prof. Dr. Suyun Lyu
Email: suyun@sunchon.ac.kr
Affiliation:
College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea.
Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon 57922, Republic of Korea.
Homepage:
Research Interests: natural product-derived compounds, cancer treatment and prevention, apoptosis pathways, cell signaling, immune modulation, phytochemicals
Summary
Cancer remains a major global health challenge, emphasizing the urgent need for innovative and effective therapies. Natural products have served as an essential foundation for modern anticancer drug development. Their unparalleled chemical diversity provides a vast resource for discovering novel compounds with enhanced efficacy and safety.
Recently, interest in anticancer drug discovery based on natural product-derived compounds has surged, driven by the increasing prevalence of cancer and the limitations of existing treatments. These compounds often offer advantages such as well-tolerated profiles and diverse mechanisms of action.
We are pleased to invite submissions to this Special Issue of BIOCELL, titled "Natural Product-Based Anticancer Drug Discovery." To align with the scope of BIOCELL, we particularly encourage studies exploring deep molecular mechanisms at the cellular level. Studies must focus on phytochemicals or specific monomers. Research on simple pure substances, crude extracts, or traditional decoctions/herbal preparations will not be considered. Suggested topics include but are not limited to:
-Molecular mechanisms of phytochemicals and natural monomers in cancer cells, with detailed analysis of signaling cascades, regulatory networks, and their influence on cellular processes such as proliferation and apoptosis;
-Identification and characterization of specific bioactive compounds, including their effects on gene expression, transcription factors, and epigenetic modifications;
-Investigation of cellular processes modulated by natural product-derived monomers, including cell-cell interactions, adhesion mechanisms, and tumor microenvironment modulation;
-Pathological mechanism studies examining how natural compounds influence inflammation, metabolic pathways, and disease progression in cancer;
-Mechanistic insights into cellular responses to phytochemical-based therapies, including biomarker identification and therapeutic signaling network analysis.
Keywords
phytochemicals, anticancer mechanisms, natural monomers, cell signaling pathways, molecular targets, cancer biology, drug discovery, cellular processes, bioactive compounds, therapeutic mechanisms
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