Open Access

ARTICLE

Modeling and Simulation of Phantom Temperature Field in Magnetic Induction Hyperthermia

J.H. Wu¹, L.Y. Zhu², J.T. Tang³

1 Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing, CHINA
2 Fuzhou Haolian Medical Technology Co., Ltd., Beijing, CHINA
3 Department of Engineering Physics, Tsinghua University, Beijing, CHINA

Computer Modeling in Engineering & Sciences 2012, 86(3), 225-240. https://doi.org/10.3970/cmes.2012.086.225

Abstract

Magnetic induction hyperthermia is one of hopeful methods for tumor therapy. In this method, several ferromagnetic seeds are needed to be implanted into the tumor. The seeds would produce energy, and cause the nearby tumor to die. Temperature prediction is significant before treatment. In addition, in clinical treatment, the tumor temperature has to be monitored in realtime. However, using as few thermometers as possible is the basic principle. Fortunately, the numerical simulation can contribute to realtime measurement. The seed temperature is modeled based on the Haider's method, which is treated as the thermal boundary in numerical simulation. We employ the lattice Boltzmann method to solve the bio-heat transfer equation. Meanwhile, three phantom experiments are carried out to evaluate the model. Thirty-two thermal seeds in total were implanted into a phantom, and three thermocouples are embedded into the specific positions to record the variation of temperature. By comparing the results of simulations and experiments, we obtain that the proposed numerical model is effective.

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Keywords

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