Open Access

ARTICLE

Drug Delivery: From a Contact Lens to the Anterior Chamber

by J.A. Ferreira², P. de Oliveira², P. Silva⁴, J.N. Murta⁵

1 This work was partially supported by Projects:PTDC/MAT/74548/2006, UTAustin/MAT/0066/2008
2 CMUC, Department of Mathematics, University of Coimbra. 3001-454, Coimbra, Portugal
3 Email of the corresponding author: ferreira@mat.uc.pt
4 Department of Physics and Mathematics, ISEC. Rua Pedro Nunes, Quinta da Nora, 3030-199 Coimbra, Portugal
5 Department of Ophthalmology, Faculty of Medicine, University of Coimbra, Portugal

Computer Modeling in Engineering & Sciences 2011, 71(1), 1-14. https://doi.org/10.3970/cmes.2011.071.001

Abstract

Mathematical models to describe drug concentration profiles of topically administered drug in the anterior chamber aqueous humor have been proposed by several authors. The aim of this paper is to present a mathematical model to predict the drug concentration in the anterior chamber when a therapeutical contact lens with the drug entrapped in nanoparticles is used.

---

Keywords

---