Open Access
ARTICLE
Web Layout Design of Large Cavity Structures Based on Topology Optimization
State Key Laboratory of Mechanics and Control for Aerospace Structures, College of Aerospace Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China
* Corresponding Author: Jialiang Sun. Email:
(This article belongs to the Special Issue: Structural Design and Optimization)
Computer Modeling in Engineering & Sciences 2024, 138(3), 2665-2689. https://doi.org/10.32604/cmes.2023.031482
Received 21 June 2023; Accepted 31 August 2023; Issue published 15 December 2023
Abstract
Large cavity structures are widely employed in aerospace engineering, such as thin-walled cylinders, blades and wings. Enhancing performance of aerial vehicles while reducing manufacturing costs and fuel consumption has become a focal point for contemporary researchers. Therefore, this paper aims to investigate the topology optimization of large cavity structures as a means to enhance their performance, safety, and efficiency. By using the variable density method, lightweight design is achieved without compromising structural strength. The optimization model considers both concentrated and distributed loads, and utilizes techniques like sensitivity filtering and projection to obtain a robust optimized configuration. The mechanical properties are checked by comparing the stress distribution and displacement of the unoptimized and optimized structures under the same load. The results confirm that the optimized structures exhibit improved mechanical properties, thus offering key insights for engineering lightweight, high-strength large cavity structures.Keywords
Lightweight design has always been a pivotal technology in aerospace. A well-known adage in this realm states, “Strive to reduce the weight of every gram, and a gram is more valuable than gold”. The lightweight design of aerial vehicles can reduce production costs and fuel consumption, bring considerable economic benefits, and effectively reduce carbon dioxide and nitrogen dioxide emissions from kerosene combustion. It is believed that for every kilogram of weight lost, an aircraft can conserve 2900 L of fuel annually [1]. Moreover, each ton of fuel conservation translates to a 3.15-ton decrease in carbon dioxide emissions [2].
Numerous large cavity structures are utilized in aerospace engineering, including thin-walled structures [3–5], wing structures [6,7], and sizable blade structures [8]. Conventional cavity support structures typically incorporate straight beam reinforcement, quadrilateral plates, equal-thickness reinforcement, and longitudinal beams. However, employing such rudimentary components leads to constraints in the design of cavity support structures. Additionally, these structural elements necessitate time-consuming and costly bolting, riveting, or welding processes. Consequently, the contemporary trend involves designing fewer structural components to achieve lightweight designs while maintaining strength, reducing costs, and enhancing efficiency. This kind of thinking leads to the development of structural unitization [9], which involves utilizing topology optimization technology to redesign the internal structure of the cavity different from the traditional structure.
Topology optimization can be divided into discrete and continuum topology optimization according to design objects [10]. As computer technology progresses and the urgent needs of engineering applications, the focus of topology optimization has gradually shifted from a discrete body to a continuum one. The year 1988 witnessed the proposal of the homogenization method by Bendsoe et al. [9]. Subsequently, the method of continuum topology optimization has experienced rapid evolution. Soon after, Bendsøe [11] and Mlejnek [12] proposed the variable density method, which reduces the complexity of homogenization and improves the 0/1 convergence. The variable density method can be divided into SIMP (Simplified Isotropic Material with Penalization) and RAMP (Rational Approximation of Material Properties). SIMP penalizes the intermediate density elements by power exponent, which has high optimization efficiency. RAMP penalizes intermediate density elements by rational function and has high stability, but the optimization efficiency is much lower than SIMP. Xie et al. [13] proposed the evolutionary structural optimization (ESO) method. This methodology is targeted at addressing the issue of gray-scale units in the SIMP approach and finds widespread application in the architectural design of edifices and bridges [14]. Xie et al. [13] proposed the level set method in 1988 and then applied it to topology optimization [15,16]. A distinct boundary delineation for a specific structure, attainable via the level set approach, necessitates the imposition of supplementary constraints, yielding increased algorithmic complexity. This, in turn, results in diminished computational proficiency. Wang et al. [17] implemented the velocity field level-set topology optimization method in MATLAB. Bourdin et al. [18] first proposed the phase-field method in 2003. Guo et al. [19] proposed the MMC/MMV method [20–22], which believes that the entity boundary can be described by explicit function. Therefore, the topology optimization issue becomes a problem of optimizing basic parameters within the topology description function [23]. In adopting this approach, the computational dimension of the optimization problem is substantially diminished. Nevertheless, the following issue involves pursuing a universal, topological descriptor function adept at representing an arbitrary array of intricate shapes. Thus, topology optimization methods have seen broad application across diverse domains, notably yielding considerable achievements in the optimization design of large cavity structures.
Many researchers have employed topology optimization technology in the optimization design of large cavity structures [24,25]. For example, by combining MATLAB and APDL programming programs, Wang et al. [26] developed the finite element-based characterization of the wind turbine blade parameter solid model. They used the SIMP method to optimize the topology of the three-dimensional blade solid model. The configuration obtained was almost identical to the traditional structure. Jensen et al. [27] introduced a topology optimization method that concurrently designs deformable functions and actuation systems in 3D deformable wing structures. Elelwi et al. [28] used ANSYS software to optimize topology on the deformed conical wing with a varying span. They roughly obtained the positioning layout of the internal fin, beam, and other wing structures. According to the optimization results, the wing structure was reconstructed, and the strength was checked to verify the structure's compliance. Aage et al. [29] proposed a computational morphology generation method for structural design with a gigabit voxel resolution two orders of magnitude higher than the reported method. This method can obtain an excellent topology optimization configuration but requires much computation. Sun et al. [30] applied the density method coupled with the integration of the equivalent static loads (ESL) method to enhance the dynamic response topology of a rotating inflatable structure. Sun et al. [31] presented an approach for the representation and optimization of the topology of thin-walled structures fitted with directional straighteners. The gradient optimization algorithm combined with design sensitivity analysis can optimize the design of straight ribbed stiffened panels on thin-walled structures.
The topology optimization design of the wing cavity can be used to improve the deformation function of the wing. Optimizing the thin-walled cylinder structure is often seen in optimizing the circumferential reinforcement layout, and the optimization results of the blade cavity are very similar to the traditional structure. No optimization design has yet been proposed for the layout of internal webs in such large cavity structures. The novelty of this work is to use the classical density method to optimize the web layout of large cavity structures in the aerospace field so as to solve the problem of large cavity structures with large mass and low stiffness and to achieve the purpose of reducing cost and increasing efficiency. We study the effects of mesh size, load magnitude, symmetry constraints, and volume fraction on the optimized results, aiming to obtain new web layouts that are different from existing ones and provide further references for the design of large cavity structures.
The subsequent sections of the paper are structured as follows. In Section 2, geometric configuration and finite element modeling of cavity structures are presented. In Section 3, the variable density method of topology optimization technology describes the topology of a large cavity structure. Density filtering and projection techniques are used to get the topology with clear boundaries. In Section 4, the web layout of large cavity structures is optimized, and the mechanical performance of the optimized results is checked. Finally, Section 5 presents several conclusions.
2 Modelling of a Cavity Structure
The four-node rectangular plate element shown in Fig. 1 for planar problems is used to discretize the cavity structures in this paper. The numbering of element nodes is A, B, C, and D. The displacement of each node is expressed as
The displacements at all nodes form a vector
The element displacement field can then be expressed as
where
Here, in the rectangular plate element,
From the physical equation of the plane problem in elasticity, the stress expression of the plate element is given by
where
In Eq. (5), E represents Young’s modulus and
2.2 Analysis of a Cavity Structure
The study conducts topology optimization of two research objects: a circular cavity and a blade section cavity, as shown in Fig. 2. The circular cavity can be used as an engine cavity, high-pressure storage tank, et al. Blade cavities are commonly found in turbine blades [32], propellers [33], et al. The circular cavity consists of a skin and an inner cavity. The geometric configuration can be determined according to the diameter of concentric circles. The blade cavity includes skin, beam, and internal cavity, and its geometry can be obtained by accurate positioning.
Generally, the blade structure is mainly composed of three parts, that is skin, spar caps, and webs. The positions of blade structural components are given in terms of straight distances and circumferential arc lengths along the cross-sectional contour. Fig. 3 shows these dimensions schematically. The main beams are divided into pressure surface beam and suction surface beam. The pressure surface beam is fitted to the inner side of the pressure surface skin, while the suction surface beam is fitted to the inner side of the suction surface skin. Together, they form the spar caps. There are two parallel supporting webs between the two spars caps.
The blade axis COS is an axis parallel to the chord of the reference cross-section. The defined angle
The width of the spar caps is defined by the circumferential arc lengths bLE and bTE. bLE represents the gap between the Sps reference line and the leading edge of the spar cap, while bTE is the distance between the Sps reference line and the trailing edge of the spar cap. The distance between the leading-edge web and the system reference line Sps is DSWLE. The distance between the trailing-edge web and the system reference line Sps is DSWTE. The above parameters vary linearly in the direction of blade length. These design parameters can be used to locate the concrete position of the spar caps and webs at any length of the blade section.
In the blade structure, the section with the largest area is cut off to obtain the blade cavity of the traditional beam web structure. This section is used as a contrast for subsequent stiffness check experiments. Then the two webs in the section are removed, the main beam and skin structure are retained, and the blade cavities are filled. Thus, one of the research objects is obtained: the blade section cavity, as depicted in Fig. 2b.
3 Topology Optimization Formulation
As a sophisticated mathematical methodology, topology optimization methodically calibrates the material distribution within a preordained spatial envelope based on specific load scenarios, constraints, and performance metrics [10,34]. In order to optimize the web layout of the large cavity, this paper employs the variable density method. The design variable, denoted as
In general, the smaller the weight, the lower the stiffness. However, when carrying out lightweight design, it is necessary to ensure that the stiffness of the structure does not decrease. Therefore, this paper chooses the flexibility of the structure as the objective function and the volume fraction as the constraint condition so that the influence of the volume fraction on the optimized configuration can also be studied. The stiffness optimization problem is mathematically expressed in the following manner:
where R is the compliance of the cavity structure, N represents the total number of elements,
To circumvent the intermediary transition region and enhance the convergence of the binary solution, the relationship between density variables
where p serves as the penalization factor and is empirically established at a value of 3. E0 =
According to Eqs. (7) and (8), the following expression elucidates the objective function R(
When multiple loading conditions occur, the single-objective optimization is transformed into multi-objective optimization. The mathematical model using the compromise programming method can typically be articulated as follows [36,37]:
where l is the number of loading cases, to establish a square root relationship and determine the weight assigned to each objective, the exponent q, which influences the weight, is set to 2.
3.2 Sensitivity and Projection
According to Eq. (9), the expressions for the sensitivities of the objective function
For Eq. (10), the sensitivities of the objective function
where
Topology optimization is often accompanied by mesh dependence and checkerboard. Grid dependence generally means that the minimum size of the optimization configuration depends on the finite element mesh. The checkerboard phenomenon refers to the alternating appearance of entities and voids in the optimal configuration, such as a checkerboard. In order to solve these problems, the general approach entails the utilization of a filtering technique [35,39,40]. The original densities
where R, defined as treble element size, is denoted as the specified filter radius, within a circular region centered at the e-th element, with a radius of R,
Nevertheless, the application of the filter may introduce gray transition domains characterized by densities between 0 and 1. Too many gray elements will blur the junction between the entity and the void, affecting material recognition. This problem can be resolved by employing the projection technique [41]. The hyperbolic-tangent function form is commonly employed in the projection function, expressed as follows:
where
In this paper, the member size constraints are considered, including the maximum and the minimum member size constraints. The small force transferring paths in the optimization results can be eliminated by the minimum member size constraint, and the minimum size of the structure can be guaranteed to be larger than the minimum member size so as to obtain a relatively uniform material distribution. On the contrary, the maximum member size constraint can provide multiple force-transferring paths and eliminate material stacking in the optimization results. Product defects caused by the manufacturing process, such as the problem of uneven heat dissipation during the casting process, can also be avoided to improve product reliability.
The minimum member size constraint is implemented by proposing two geometric constraints by a three-field scheme [42,43], also known as the filtering-threshold topology optimization scheme. The three fields are formed by filtering and projection transformation of the design field in turn, and the transformation process can be summarized as
where
The maximum member size constraint is based on morphological operators [44], implemented through the erosion and dilation operations, two morphological operations. By erosion operation, solid element sizes smaller than a given structural element will be eliminated. By dilation operation, void element sizes smaller than a given structural element will be eliminated. With Heaviside projections and filtering, both operations can be achieved. The conditions guaranteeing the maximum member size on the solid and void can be written as
where
where V is the vector of the element volume.
4.1 Topology Optimization of a Circular Cavity under Concentrated Load Condition
In this case, the layout optimization of a circular cavity internal web structure under concentrated load condition is studied. As shown in Fig. 4, the outer diameter and skin thickness of the circular cavity are 150 and 7.5 mm, respectively. A pair of concentrated forces F with the same magnitude of 1 N and opposite directions act on the vertices in the y-direction of the cavity.
The circular cavity is discretized into 18020 rectangular plate elements with a side length of 1 mm. The material properties of the internal cavity and the skin are identical. The selection of the objective function was guided by the criterion of minimum compliance. A volume fraction of 25% is assigned for
Fig. 5 presents the optimization result along with the iterative histories of the volume ratio and objective function. The black area represents the material domain, while the white area is the void one. The influence of four factors, that is, mesh size, load magnitude, symmetry constraint, and volume fraction, on the optimization results are investigated, respectively.
Firstly, an investigation is conducted to explore the influence of mesh size on the optimization results. When employing a side length of 2 mm for the elements, there are 4613 plate elements. The ensuing optimization outcome corresponding to this configuration is visually presented in Fig. 6a, while the iterative histories of the volume ratio and objective function are graphically depicted in Fig. 7a, Figs. 5a and 6a showcase the optimization results, revealing an identical structure that maintains four supporting webs in the y-direction, which retains four supporting webs in the y-direction. As the element size increases, the number of elements decreases, reducing the iteration steps from 749 to 430. Although the 1 mm-size element model has more iteration steps, its optimization result is more refined. The similar converging trends displayed by the volume fraction and objective function corroborate the notion that the mesh size has little impact on the optimization result. With the aim of obtaining more refined results, other subsequent examples in this paper use an element size of 1 mm.
Secondly, an investigation is conducted to explore the impact of load magnitude on the optimization result. The concentrated force F is set to 100 N for this case. Fig. 6b illustrates the optimization result, while Fig. 7b presents the historical progression of iterations for both the volume ratio and objective function. The optimization results and iteration curves are almost the same as those in Fig. 5. Based on the analysis, it can be inferred that the optimization model remains relatively unaffected by variations in the magnitude of the applied load. To facilitate result comparison, the load magnitude is normalized. In the following examples, the load magnitude is set as 1 N.
Thirdly, to examine the impact of a symmetric constraint on the optimization results and facilitate industrial manufacturing, symmetry constraint is incorporated into the optimization outcome. The final result mandates symmetry around both the x-z and the y-z plane as a fundamental requirement. Fig. 6c delineates the optimization results, whereas Fig. 7c depicts the iterative progression for both the volume ratio and the objective function of the progression of iteration curves. Compared with Fig. 5a, the supporting webs in Fig. 6c are straight and uniform in thickness. However, on either side, there are two straight narrow webs whose dimensions are less than the optimized minimum size. This is the result of the projection technique eliminating many elements with densities less than 0.5.
Fourth, to eliminate these two narrow webs and further reduce the weight, the volume fraction is reduced to 15%. At the same time, the maximum and minimum member sizes are adjusted to 6 and 3 mm. Fig. 6d delineates the optimization results, whereas Fig. 7d provides a detailed depiction of the iterative progression for both the volume ratio and the objective function. In the results, the number of webs increased to 5, and the arrangement is symmetrical. The slender webs vanish, while the volume fraction effectively satisfies the imposed volume constraint.
For the purpose of authenticating the correctness of the optimization results, the ABAQUS software has been employed to compute the displacement and stress of the model both before and after optimization. Since the volume fraction constraint during topology optimization is set as 0.15, to ensure the same mass of the two structures before and after optimization, the thicknesses of the optimized and the unoptimized structures are set to be 1 and 0.15 mm, respectively.
Under the same mass condition, the optimized circular cavity structure demonstrates substantial enhancement in mechanical properties, as indicated by the results. Table 1 and Fig. 8 collectively exhibit the results of mechanical analysis for the two structures when subjected to a concentrated force. The unoptimized structure exhibits a maximum stress of 2.632 MPa, along with a maximum displacement of 5.323 × 10−5 mm. After optimization, the maximum stress is 0.786 MPa, and the maximum displacement is 3.133 × 10−5 mm. The loading point of the unoptimized structure manifests evident stress concentration and substantial displacement. Through optimization, the stress concentration at the loading point is effectively mitigated, with maximum stress reduced by 70.13%. The structure achieves a significant 41.14% reduction in maximum displacement. Under the same mass condition, the optimized circular cavity structure demonstrates substantial enhancement in mechanical properties, as indicated by the results.
4.2 Topology Optimization of a Circular Cavity under Uniform Load Condition
In this case, the layout optimization of the web structure of a circular cavity under the uniform load is studied. The concentrated load F is transformed into the uniformly distributed load q. The value of q satisfies the formula.
where l is the arc length in the load range, this loading mode is closer to the force situation of the cavity structure in actual work, which is shown in Fig. 9.
The volume constraint equals 0.25. The member size constraints are also considered, with the maximum and minimum member sizes being 12 and 6 mm, respectively.
Fig. 10a displays the optimization result, while Fig. 11a provides a detailed depiction of the iterative progression for both the volume ratio and the objective function. With the expansion of the force's loading range in the x-direction, a supportive structure oriented within the same axis emerges in the optimization result. The y-direction support structure presents a complex and disordered network structure. According to the volume fraction iteration curve, the optimization result satisfies the volume constraint.
In order to facilitate industrial manufacturing, the symmetric constraint is considered. Fig. 10b presents the optimization results, while Fig. 11b provides a detailed depiction of the iterative progression for both the volume ratio and the objective function. Compared with Fig. 10a, the web in the y-direction in Fig. 10b is missing. Prior to the disordered network, the structure is effectively eliminated, making the overall structure more symmetrical. It is helpful to ease production and manufacturing challenges.
For the purpose of weight reduction, the volume fraction parameter of 0.15 has been set. Accordingly, the maximum and the minimum member size are set as 6 and 3 mm. The optimization result and convergence profiles of the volume ratio and objective function are visualized in Figs. 10c and 11c, respectively. The result indicates a symmetric arrangement of the web. A new web layout of the optimization result consists of three vertical webs and one horizontal web. The volume fraction meets the volume constraint.
The optimization results depicted in Fig. 10c have undergone an examination of their mechanical properties. To ensure the same weight for the two structures, the thickness of the optimized and unoptimized structures are set as 1 and 0.15 mm, respectively. The mechanical performance of the optimized cavity structure can be verified by comparing the displacement and stress distribution of two cavity structures under the same load q.
The simulation results of the unoptimized and optimized structures are shown in, thereby enhancing the overall structural stiffness of the cavity.
The unoptimized structure exhibits a maximum stress of 0.114 MPa and a vertex displacement in the y-direction of 3.133 × 10−5 mm. After optimization, the maximum stress is 0.095 MPa. The vertex has experienced a displacement of 1.992 × 10−5 mm in the y-direction. The maximum stress is reduced by 17.15%, and the displacement of the vertex is reduced by 17.17% in Table 2. The results in Fig. 12 indicate that the horizontal and vertical webs effectively inhibit the displacement of the cavity, thereby enhancing the overall structural stiffness of the cavity.
4.3 Topology Optimization of a Blade Cavity for Web Layout Design
In order to provide a new structure with a more robust web layout in the blade cavity, this case takes the blade cavity as the research object and studies the layout optimization of the web structure in the blade cavity. Fig. 13 illustrates the conventional beam web arrangement and the corresponding design domain. The blade airfoil is SR152, with a chord length of 150 mm. The thickness of blade skin and spar caps are 3 and 1.5 mm. The spar caps width equals the sum of bLE and bTE, that is, 27 mm. The skin and inner cavity share the same material composition, with the inner cavity being considered the design domain.
According to the results in Section 4.1, the element size is 1 mm, so 15,459 plate elements are used to discretize the blade cavity structure. The turbulence model Spalart-Allmaras [45] can be calculated to get the pressure distribution on the airfoil section. When the installation angle of the blade is 12 degrees, the pressure curve of the suction and pressure side is shown in Fig. 14. The pressure on both sides is divided into two working conditions, shown in Fig. 15. In the condition I, the suction side beam is immobilized and the load is imposed on the pressure side. In contrast, in condition II, the pressure side beam is immobilized and the load is imposed on the suction side. The minimum weighted compliance for the two conditions is the objective function with the convergence tolerance ratio of
Considering the conventional blade cavity web structure,
As illustrated in Fig. 16, the optimization results without and with symmetric constraints. Fig. 17 depicts the histories of the volume ratio and objective function iterations. Fig. 16a, irregular web structures differ from traditional web layouts. The web structures are mainly concentrated in the middle part of the cavity. Like the traditional web layout, no web is at the trailing edge. After adding the symmetric constraint, in Fig. 16b, the structure presents a relatively novel symmetrical network layout. The webs in chord direction, vertical direction, and 45° angle with vertical direction appear simultaneously. Fig. 17 shows that the results satisfy the volume constraint after convergence.
As shown in Figs. 18 and 19, the mechanical simulation results of the unoptimized model and the optimized model under two working conditions are presented. In the condition I, Table 3, the detailed data, the unoptimized model exhibits a maximum stress of 6.408 MPa and a maximum displacement of 5.361 × 10−3 mm. The optimized model exhibits a maximum stress of 3.646 MPa and a maximum displacement of 4.469 × 10−3 mm. The maximum stress and displacement decrease by 43.1% and 16.64%, respectively. Compared with Figs. 18a, 18b, 19a, and 19b, the stress on the skin exhibits improved uniformity after optimization. The stress concentration is effectively relieved. The skin displacement near the pressure side beam before and after optimization are 5.43 × 10−4 mm and 4.11 × 10−4 mm, respectively, and the displacement is reduced by 24.31%.
In condition II, Table 4, the detailed data, the maximum stress, and the maximum displacement of the unoptimized model are 1.707 MPa and 3.513 × 10−3 mm. In the optimized model, maximum displacement and maximum stress are 1.777 MPa and 1.693 × 10−3 mm, respectively. However, the maximum stress increases by 4.1%, Figs. 18c, 18d, 19c and 19d demonstrate that the load acting on the pressure side is better transmitted to the web, which also significantly reduces the displacement of the blade. The maximum displacement is reduced by 51.81%. The skin displacement near the suction side beam before and after optimization is 0.0332 and 0.0293 mm respectively, which decreased by 11.75% after optimization. The results demonstrate a substantial enhancement in the mechanical properties of the blade cavity under both condition I and condition II.
In this paper, the web layout design of large cavity structures based on topology optimization is carried out. Detailed topology of the large cavity structures is described using SIMP. By using element densities as design variables, the web layouts are optimized for circular and blade cavities by minimizing structural compliance and constraining volume fraction. Optimizing the circular cavity structure involves investigating two load conditions: concentrated and distributed loads. Additionally, the influence of mesh size, load magnitude, symmetry constraint, and volume fraction on the optimization results is explored. The findings reveal that mesh size and load magnitude have negligible influence on the optimized configuration. Symmetry constraints can make the result more beneficial to put into production. The reduction of volume fraction can further reduce the structural weight. The optimized design model is established according to the design parameters of a commercial 4.3MW-SR152 blade. The optimized result shows that the web layout differs from the traditional ones with webs in chord direction, vertical direction, and 45° angle with vertical direction appearing simultaneously. The mechanical properties of the structures before and after optimization are compared. It reveals that the optimized structure is stiffer than its unoptimized counterpart while maintaining the same mass, with varying degrees of improvement. For the circular cavity, the maximum displacement is reduced by 41.14% in the concentrated load case, and the vertex displacement is reduced by 17.17% in the uniformly distributed force case. The maximum displacement of the blade cavity structure is reduced by 51.81% in condition I and 16.64% in condition II, respectively. In addition, stress concentration is also relieved with the maximum stress of the circular cavity structure reduced by 70.13% in the concentrated load case and 17.15% in the uniformly distributed force case. In condition II, a notable 43.1% reduction is observed in the maximum stress of the blade cavity structure.
Acknowledgement: This paper’s logical organisation and content quality have been enhanced, so the authors thank anonymous reviewers and journal editors for assistance.
Funding Statement: This work was supported in part by the National Natural Science Foundation of China and the Natural Science Foundation of Jiangsu Province. It was also supported in part by Young Elite Scientists Sponsorship Program by CAST.
Author Contributions: The authors confirm contribution to the paper as follows: study conception and design: Xiaoqiao Yang, Jialiang Sun, data collection: Xiaoqiao Yang, analysis and interpretation of results: Xiaoqiao Yang, Jialiang Sun, draft manuscript preparation: Xiaoqiao Yang, Jialiang Sun and Dongping Jin. All authors reviewed the results and approved the final version of the manuscript.
Availability of Data and Materials: The data that support the findings of this study are available from the first and corresponding authors upon reasonable request.
Conflicts of Interest: The authors declare that they have no conflicts of interest to report regarding the present study.
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