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Magnetic Field Effect and Heat Transfer of Nanofluids within Waveform Microchannel

by Mehdi Moslemi1, Motahare Mahmoodnezhad1, S. A. Edalatpanah1,*, Sulima Ahmed Mohammed Zubair2, Hamiden Abd El-Wahed Khalifa2,3

1 Ayandegan Institute of Higher Education, Tonekabon, Iran
2 Department of Mathematics, College of Science and Arts, Qassim University, Ar Rass, Saudi Arabia
3 Operations Research Department, Faculty of Graduate Studies for Statistical Research, Cairo University, Giza, Egypt

* Corresponding Authors: S. A. Edalatpanah. Email: email,email

(This article belongs to the Special Issue: Numerical Methods in Engineering Analysis, Data Analysis and Artificial Intelligence)

Computer Modeling in Engineering & Sciences 2023, 134(3), 1957-1973. https://doi.org/10.32604/cmes.2022.021481

Abstract

In this research, a numerical study of mixed convection of non-Newtonian fluid and magnetic field effect along a vertical wavy surface was investigated. A simple coordinate transformation to transform wavy surface to a flat surface is employed. A cubic spline collocation numerical method is employed to analyze transformed equations. The effect of various parameters such as Reynolds number, volume fraction 0-, Hartmann number, and amplitude of wave length was evaluated in improving the performance of a wavy microchannel. According to the presented results, the sinusoidal shape of the microchannel has a direct impact on heat transfer. By increasing the microchannel wave amplitude, the Nusselt number has risen. On the other hand, increasing the heat transfer in the higher wavelength ratio corrugated channel is seen as an effective method of increasing the heat transfer, especially at higher Reynolds numbers. The results showed that with increasing Hartmann numbers, the flow line near the wall becomes more regular and, according to the temperature gradient created, the Nusselt number growth.

Keywords


1  Introduction

The use of advanced and efficient cooling systems to sustain the reliable and effective operation of devices with microelectronic parts and the like is inevitable. The dramatic increase in heat transfer in microchannels has led to their use as heat dissipation devices in microelectronic equipment. High heat transfer, small size, the need of a small amount of cooling fluid is the characteristics of microchannels. Expanding the surface of cooling devices by changing the geometry of heat channels, such as corrugating the surface of the channel, causes changes in the efficiency of heat exchangers. Changing the flow rate or suspending solid particles in a fluid is also one of the methods used to increase heat transfer. Creating a magnetic field according to the current regime can also increase or even decrease the amount of heat transfer. In the following, the studies that have been done in this field were reviewed. Most researches have shown that with the addition of nanoparticles with relatively high thermal conductivity to the base fluid, the thermal performance of the nanofluid will be enhanced [1]. Heris et al. [2] used water-aluminum oxide nanofluids in a triangular cross-sectional channel under constant heat flux boundary conditions in the wall to investigate the forced displacement heat transfer in a laminar-flow process in the laboratory. The outcomes proved the pure water lab heat transfer coefficient is lower than the nanofluid laboratory heat transfer coefficient. Furthermore, it is more distinguished than the one calculated in theory. Nanofluids have particular properties that distinguish them entirely from a mixture of two-phase fluids in which the particles are micro or millimeter in size [3]. Zarringhalam et al. [4] investigated the effect of Reynolds number and volume fraction on pressure drop and heat transfer coefficient of copper oxide and water of nanofluid experimentally. Results revealed that the heat transfer coefficient of the base fluid is commonly lower than the nanofluids. Observations additionally showed growing the volume fraction coefficient and Reynolds number, improving the heat transfer coefficient and the Nusselt number. However, the magnitude of this improvement is more evident in lower Reynolds. Öğüt et al. [5] studied the heat transfer of turbulent nanofluid on corrugated trapezoidal plate heat exchangers with boundary conditions on a wall with constant heat flux numerically. Examining the impacts of nanofluids on the heat transfer flow and rate, they observed growing nanoparticle concentration rises heat transfer. In addition, they observed using nanofluids in the trapezoidal channel improves the performance of heating systems and leads to the design of more dense and small heat exchangers. Shehzad et al. [6] used the Bangirno model in a wavy channel to examine nanofluid free displacement heat transfer effects in which thermos diffusion and the brown motion simultaneous impacts are analyzed. Peng et al. [7] investigated nanofluids heat transfer using three homogeneous single and two-phase Euler-Euler and two-phase Euler-Lagrange methods and compared them with similar experimental results. They found that among the used models, the Euler-Lagrange model presented the most precise analysis, while the single-phase had the lowest precision. Zabilhi et al. [8] conducted a simultaneous experimental and numerical study for water-aluminum oxide nanofluids in the form of slow flow in an equilateral triangle cross-section channel and constant heat flux, which resulted in increased heat transfer rate with increasing nanoparticle volume concentration. Ducts with non-flat plates have many applications because they increase the level of heat transfer. Among these channels are sinusoidal channels that enhance heat transfer and have less effect on the unfavorable pressure gradient along the channel. Wavy channels are found in many engineering applications [9]. Chai et al. [10] increased the rate of microchannel heat transfer by considering various ribs in the lateral canal walls. Moreover, with rising Reynolds number, the use of different ribs due to the improvement in pressure drop in the microchannel misses its advantage as an efficient method of improving heat transfer. Ahmed et al. [11] investigated the flow of a nanofluid in a corrugated channel using numerical methods and changing the Reynolds number (between 100 and 400) and changing the volume percentage of nanoparticles (from zero to 5%). They examined the influence of these parameters on heat transfer. Zhou et al. [12] presented the best length-to-amplitude ratio utilizing the finite volume method and corrugated wall geometric simulation as the main factor to improve the efficiency of heat transfer. In one study, Moon et al. [13] applied three-dimensional numerical simulations for investigating the development of heat transfer in micro-and multi-harmonic corrugated channels at the square cross-section. With more attention to channel surface geometry effect and using the Nusselt number ratio in wavy channels directly, they analyzed the cold water parametrically in different Reynolds. The more beneficial form of a corrugated microchannel heat sink was proposed by Lin et al. [14]. They changed the amplitude and wavelength by the flow direction. The formation of vortices increased heat transfer and was connected to the curved walls, which caused the cooling to mix and improved the heat transfer among the channel wall and the coolant.

Kirsch et al. [15] investigated the performance of corrugated ducts pressure drop and heat transfer. Due to the current created by the wave structure, they showed that short-wavelength channels have a higher pressure drop than high-wavelength channels, and increasing the wavelength improves the heat transfer performance. Skullong et al. [16] studied the solar-air heating channel heat transfer using corrugated grooves with a pair of trapezoidal fins located on the absorber plate. It showed that corrugated grooves with a pair of trapezoidal fins caused a notable increase in heat transfer compared to a smooth channel, and both trapezoidal fins alone displayed extremely higher heat transfer but the corrugated grooves caused a significant pressure drop. Yadav et al. [17] examined increasing a microchannel heat transfer using a large surface area. Comparing rectangular microchannels with cylindrical microphones, they concluded that the performance of the microchannel heat transfer was better than microphones. Furthermore, in the presence of wide surface microchannels, the average surface temperature decreases. The magnetic field affects both forced and free movement. The use of a magnetic field in free movement reduces the velocity near the wall and lessens heat transfer [18]. Malekpour et al. [19] studied the impact of magnetic fields on free movement in a triangular chamber. They utilized Hartmann numbers up to 80 to the chamber and noted that developing the Hartmann number decreased the fluid velocity in the triangular chamber and reduced free movement heat transfer. Unlike free displacement, in forced displacement, the magnetic field flattens the velocity profile, which increases velocity near the channel walls and enhances the heat transfer coefficient. The nanofluid particles are orients regularly by the magnetic field that result in more communication between the nanoparticles. Consequently, in a nanofluid stream, the utilization of a favorable magnetic field can dramatically increase heat transfer [20]. Aminfar et al. [21] examined the non-uniform magnetic field impact of electric current in a magnetic fluid. They determined that the magnetic field improves the heat transfer coefficient up to 22% and prevents nanoparticles from settling. Nourazar et al. [22] numerically analyzed the nanoparticles’ flow under a magnetic field on a flat plate. Motozawa et al. [23] experimentally investigated the impact of a magnetic field on the slow current heat transfer in a rectangular channel. Their results confirmed that the magnetic field application increases the heat transfer coefficient and enhances the heat transfer up to 20%. Çelik [24] examined the impact of a magnetic field on current in a channel with a rectangular cross-section and examined up to Hartmann 1000. Rashidi et al. [25] examined nanofluids’ conduction and heat transfer in a vertical channel with a sinusoidal wall under the impact of a magnetic field and discovered the increase in gradient number for nanofluids with different volume fractions, develops the average Nusselt number. In addition, with raising the Hartmann’s number, the average Nusselt increases. Heidary et al. [9] numerically studied the heat transfer and flow field in a nanofluid wavy channel and showed that the heat transfer in the channels could be enhanced by 50% with adding nanoparticles and usage wavy horizontal walls. Al-Zurfi et al. [26] numerically investigated the flow field and heat transfer performance in fixed and rotating wave channels with different shapes. They found that as the rotation velocity increased, the lower wall heat transfer coefficient increased significantly,while the upper wall heat transfer coefficient increased slightly. Alsabery et al. [27] numerically investigated the mechanisms of increasing convective heat transfer with two-phase water nanofluids in a three-dimensional horizontal wavy channel with high and low wavy surfaces with uniform temperature and adiabatic conditions, respectively. The results indicated that nanofluid flow in the undulating channel is higher, especially at higher volume fractions of nanoparticles and Reynolds numbers. Also, higher convective heat transfer is achieved by increasing the flow mixing due to the increase in oscillation frequency. Mehta et al. [28] evaluated the thermo-fluidic and entropy generation characteristics for laminar forced convective flow through a wavy channel at different Prandtl (Pr) numbers. Their results indicated that the channel performance coefficient (PF) with different Prandell numbers showed non-uniform behavior at lower Reynolds number and uniform behavior at higher Reynolds number. Elsafy et al. [29] investigated the performance of three fluids with forced convection in a wave channel. Their results revealed that the wavy channel provides better heat gain than the straight channel with the same dimensions. Porous materials enhanced heat extraction at the expense of pressure drop. 1% TiO2 nanofluid in water provided the highest performance evaluation criteria.

In this paper, the forced convection of nano fluids flow in the presence of a magnetic field in the corrugated microchannel was examined. The novelty of this study is use of simple coordinate transformation to transform wavy surface to flat surface. The transform stream vorticity and energy equations are solved by Spline Alternating Direction Implicit (SADI) method. Since the SADI method can evaluate the spatial derivative terms directly without any finite difference discretization, the gradient boundary conditions may be represented more accurately, and irregular boundaries are easier to deal with. By considering the boundary conditions, the effect of parameters such as nanofluid volume fraction, wave amplitude, Hartmann number, Reynolds number, and magnetic field in the wavy microchannel have been investigated. The innovation of this paper is the use of mapping in corrugated microchannels to solve vortex flow equations in forced heat transfer. By drawing medium and local Nusselt diagrams in different modes of these parameters and comparing them with each other, we have tried to provide the most optimal model for increasing heat transfer in a corrugated microchannel.

2  Problem Mathematical Formulation

Fig. 1 shows the coordinate system and physical model of the problem. Viscous dissipation is insignificant and is not considered. The above assumptions are designed to maintain the theoretical model as simple as possible. In this coordinate system, x is along the wavy surface in the flow direction, and y is the flow perpendicular. The equation of wavy surface equation is as follows:

S(X)=L+αsin(π(x¯xs¯)L).(1)

where L is average vertical distance from the center of the channel and α is the magnitude of the wave length domain.

images

Figure 1: The temperature is at the wavy surface (Tw) and the magnetic field the microchannel at an angle γ

The upper and lower wavy surfaces correspond to constant temperature Tw, which is above the ambient temperature T. The beginning and end of the microchannel are flat, the wall of which is adiabatic in this part. The nanofluid temperature is assumed to be T0. The fluid flow is under uniform magnetic field B0 so that γ is the direction of the magnetic field with the horizontal axis and in this study, γ = π/ 6.

The governing equations in this method for an uncompressible flow, stable and two-dimensional are presented as follows:

u¯x¯+v¯y¯=0,(2)

u¯u¯x¯+v¯u¯y¯=1ρnfpx¯+v¯nf(2u¯x¯2+2u¯y¯2) - σnfu¯ρnfB02sin2γ+σnfv¯ρnfB02sinγcosγ,(3)

u¯v¯x¯+v¯v¯y¯=1ρnfpy¯+νnf(2v¯x¯2+2v¯y¯2)σnfv¯ρnfB02cos2γ+σnfu¯ρnfB02sinγcosγ,(4)

u¯Tx¯+v¯Ty¯=αnf(2Tx¯2+2Ty¯2).(5)

In the above equations, u and v are the velocities of the fluid in the x and y directions, ρnf, p, T and B0 are density, pressure, the temperature of the fluid and the magnetic field, respectively.

The effective density, dynamic viscosity, and nanofluids heat capacity are represented as follows [3033]:

ρnf=ρf(1ϕ)+ρsϕ,(6)

μnf=(1+2.5ϕ)μf,(7)

(ρCp)nf=(ρCp)f(1ϕ)+(ρCp)sϕ.(8)

In this paper, assuming the spherical shape for nanoparticles, the Maxwell-Garnet relationship is used to determine the thermal conductivity, which is determined as follows [34]:

knf=(ks+2kf2ϕ(kfks)ks+2kf+ϕ(kfks))kf.(9)

Also, the effective nanofluid electrical conductivity from the Maxwell relation is written as follows [35]:

σnfσf=1+3(σsσf1)ϕ(σsσf+2)(σsσf1)ϕ.(10)

The flow and rotation functions are described as follows:

v¯=ψx¯.(11)

ωz=(v¯x¯u¯y¯).(12)

The flow function in the continuity equation and the rotation equation is obtained from removing the pressure gradient among the momentum equations and extracting Eq. (5) in the y-direction and decreasing it from the derivative of Eq. (6) in the x-direction as follows:

u¯Ωx¯+v¯Ωy¯=µnfρnf(2Ωx¯2+2Ωy¯2)+σnfρnfB02[cos2γv¯x¯+ sinγcosγu¯x¯+ sin2γu¯y¯ sinγcosγv¯y¯].(13)

Dimensional variables for dimensionless equations are defined as follows:

ω=ΩLU,ψ=ψUL,u=u¯U,v=v¯U,=x¯L,y=y¯L,θ=TTTTW, Ha=LB0σfµf, Re=u L ν.(14)

where Ha and Re are the Hartmann and Reynolds number of the base fluid, respectively. Also, the thermophysical properties of the copper oxide and base fluid are given in Table 1.

images

By placing dimensionless variables in the equations of continuity, momentum and energy are as follows:

2ψx2+2ψy2=ω,(15)

uωx+ vωy=1Re(µnf/µfρnf/ρf)(2ωx2+2ωy2)+(σnf/σfρnf/ρf)Ha2Re[cos2γ2ψx2+sin2γ2ψy2+2 sinγcosγ2ψy],(16)

uθx+θy=1Re Pr(knf/kf(ρCp)nf/(ρCp)f)(2θx2+2θy2).(17)

The wavy surface becomes a flat surface, to solve the surface we use the following transform:

ξ=,η=ys(x).(18)

Therefore, using it in an equation, the wavy surface turns to a flat surface. These equations are

2ψξ2+(ηx2+ηy2)2ψη2+2ηx2ψξη+(ηxx+ηyy)ψη=ω(19)

u(ωξ+ηxωη)+vηyωη=(1+2.5ϕ+6.2ϕ2)((1ϕ)+ρsρfϕ)(1Re)[2ωξ2+(ηx2+ηy2)2ωη2+2ηx2ωξη+(ηxx+ηyy)ωη]+Ha2Re[+3(σsσf1)ϕ(σsσf+2)(σsσf1)ϕ](1(1ϕ)+ρsρfϕ)×[cos2γ(ηx22ψξ2+2ηx2ψξη+ηx22ψη2+ηxxψη)+sin2γ(ηy22ψξ2+ηy22ψη2)+2sinγcosγ(ηy2ψξη+ηxηy2ψη2+ηxyψη)](20)

u(Tξ+ηxTη)+vηyTη=1RePr(ks2ϕ(kfks)+2kfks2ϕ(kfks)+2kf(1ϕ)+(ρCp)s(ρCp)fϕ)(2Tξ2+(ηx2+ηy2)2Tη2+2ηx2Tξη+(ηxx+ηyy)Tη).(21)

where the boundary conditions are as follows:

u=ηyψη,v=(ψξ+ηxψη),ηy=1s(x),ηx=ys(x)s(x)2,ηxx=y(2s2+ss)s(x)3,ηyy = 0(22)

η=1,u=v=0ψ= cte=1,θ=1On the wall(23)

η=0,ψ=ω=0θη=0Microchannel center(24)

ψ=32(ηη33)ω=3y,,θ=0Microchannel input(25)

ωξ=0ψξ=0uξ=0vξ=0θξ=0Microchannel output(26)

The local Nusselt number is described as follows:

Nux=(T/n)x¯TwT0.(27)

∂T/∂n is a derivative of the vector perpendicular to the corrugated surface of the object, which is defined as follows. Eventually, after dimensioning and changing the corrugated surface variable to smooth, the Nusselt number is written as follows.

The mean Nusselt number is determined by combining the local Nusselt numbers on the upper wall of the microchannel as follows [37]:

Tn=(Tx)2+(Ty)2.(28)

Nux=(ηx2+ηy2)1/2θη(knfkf),(29)

Num=1S¯x0xLNuxdS=1S¯(knfkf)x0xL(ηx2+ηy2)1/2θηdξ(30)

which in the above relation S¯ is equal to

S¯(ξ)=x0xL(1+S¯2)dξ.(31)

The coefficient of skin friction Cf is also defined as follows [37]:

Re Cf=(ηy2ηx2)2ψη2.(32)

ReCf=(ηy2ηx2)2ψη2.(33)

3  Numerical Solution Method

Having the boundary condition, the spline alternating direction implicit method [38,39] has been used to solve the governing dimensionless differential Eqs. (19)(21). Using the false transient technique, Eqs. (19)(21) can be written in the following form:

φi,j=Fi,jn+Gi,jmi,jn+1+Si,jmi,jn+1.(34)

where represents u or θ or the first and second derivatives of with respect to y, i, j refer to the computational nodes where n is time step. Fi,j, Gi,j and Si,j are the known coefficients evaluated at the previous time step. Eq. (34) may be written in tri-diagonal form using cubic spline collocation [39].

Ai,jΩi.j1+Bi,jΩi.j+Ci,jΩi.j+1=Di,j(35)

where Ω represents u or θ or first and second derivative. Eq. (34) can be solved, using Tomas algorithm.

In this research, the iteration process is continued until the convergence criterion, is achieved

Ωi,jn+1Ωi,jnΩmaxn<5×105.(36)

4  Results and Discussions

A very important issue in numerical simulation is to ensure that the number of mesh points is adequate. To achieve enough points, we start the calculation with a suitable mesh and gradually increase the mesh points number, by that from several points onwards, the effect of the mesh on the results is negligible for the above problem, 50 × 360, 60 × 740, 75 × 1000 and 80 × 1480 mesh has been used. To diminish the computational cost of the software, 75 × 1000 mesh has been used (Fig. 2).

images

Figure 2: Investigation of the effect of network number on surface friction coefficient at α = 0.2, Re = 300, Pr = 6.83

Verifying the code results are examined with the values of the research of Wang et al. [37]. It can be seen that in Figs. 3 and 4, the coefficient of surface friction and local Nusselt obtained from the present study are very close to the outcomes of Wang et al. [37].

images

Figure 3: Results of this study compare with Wang et al. [37] for friction coefficient at Re = 500, Pr = 6.83

images

Figure 4: Results of this study compare with Wang et al. [37] for local Nusselt in Re = 500, Pr = 6.83

Figs. 5 and 6 show the microchannel wave amplitude parameter impact on local and mean Nusselt number at Ha = 5, Re = 500, and volume fraction of 0.1. Medium Nusselt in wavy microchannels with shorter wavelengths, such as α = 0.1, are only slightly larger than planar microchannels, whereas when the wave amplitude increases to 0.2 and 0.3, the average Nusselt suddenly increases dramatically. This occurs due to the creation of a secondary current that causes the fluid to rotate and create a vortex, and as the amplitude of the wave rises, the flow line becomes more vortexes. In Fig. 5, in the convergent part of the microchannel, where the channel height is minimal, the local Nusselt number also increases due to the increase in velocity. While in the part of the channel where the height is maximum, the local Nusselt number also decreases due to the reduction of the velocity slope and temperature.

images

Figure 5: Local Nusselt diagram in the wave amplitude of α = 0, 0.1, 0.2, 0.3

images

Figure 6: The average Nusselt diagram in the amplitude waves of α = 0, 0.1, 0.2, 0.3

Fig. 7 shows how the vortex forms at the peak of the wave and the stream line in the microchannel at the wavelength of 0.2. As it is known, the proximity of the stream lines in the wave fall part is more than the wave rise part.

images

Figure 7: How to form a vortex in the wavy part of the microchannel in the wave amplitude of 0.2

Figs. 8 and 9 show the changes in the impact of volume fraction on mean and local Nusselt at Reynolds number 200, wavelength 0.2, and Prandtl number 6.93. Raising the volume fraction of the base fluid nanoparticles improves the effective thermal conductivity of the nanofluid. As a result, Nusselt number and heat transfer are improved.

images

Figure 8: Local Nusselt diagram for different volume fractions, Re = 200 and Ha = 10

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Figure 9: Diagram of medium Nusselt of different volume fractions, Re = 200 and Ha = 10

Figs. 10 and 11 show the flow line diagram in Reynolds number 200, wavelength 0.2 and volume fraction 0.1 and various Hartmann numbers. As the Hartmann number rises, the probability of a vortex in the wall decreases, and this is because of the gross velocity near the wall. Fig. 12 indicates the stream and temperature contour. Therefore, by increasing the Hartmann number near the wall, the gradient of the temperature rises. Consequently, the local and mean Nusselt number (shapes) increases and the heat transfer rate raises.

images

Figure 10: Local Nusselt diagram in different Hartmann numbers

images

Figure 11: Mean Nusselt diagram in different Hartmann numbers

images

Figure 12: Stream contour (a) and temperature contour (b) for different Hartmann numbers

5  Conclusion

In this research, the forced convection heat transfer with nanofluid flow in a wavy microchannel in the presence of a magnetic field was examined numerically. A simple transformation and the spline alternating direction implicit method (SADI) were employed to analyze. Nanoparticle volume fraction, wave length amplitude, and Hartmann number impact on heat transfer properties and fluid stream were investigated. Outcomes indicate that adding high conductivity nanoparticles to the base fluid improves the heat transfer property of the fluid, which raises the average Nusselt number of a microchannel. This upward trend intensifies with the increment in Reynolds number because of the formation of larger vortices. With microchannel deformation from parallel to wavvy due to the creation of secondary current in the corrugated parts of the microchannel, an increasing trend of heat transfer is observed. The corrugation of the microchannel also increased the nanofluid efficiency in heat transfer. In addition, outcomes show that by increasing Hartmann number, the velocity of the flow near the corrugated wall of the microchannel rises and the velocity profile near the wall becomes smoother, which improves the nature of the heat transfer. As the Reynolds number rises, the more inertial force is applied to the current and the effect of the Hartmann number increases. These results, which have been obtained by making changes in various parameters, are beneficial in designing a compact and optimal heat exchanger.

Acknowledgement: The researchers would like to thank the Deanship of Scientific Research, Qassim University, for funding the publication of this project.

Funding Statement: This work was partially supported by College of Science and Arts, Qassim University, Saudi Arabia.

Conflicts of Interest: The authors declare that they have no conflicts of interest to report regarding the present study.

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Cite This Article

APA Style
Moslemi, M., Mahmoodnezhad, M., Edalatpanah, S.A., Zubair, S.A.M., Khalifa, H.A.E. (2023). Magnetic field effect and heat transfer of nanofluids within waveform microchannel. Computer Modeling in Engineering & Sciences, 134(3), 1957-1973. https://doi.org/10.32604/cmes.2022.021481
Vancouver Style
Moslemi M, Mahmoodnezhad M, Edalatpanah SA, Zubair SAM, Khalifa HAE. Magnetic field effect and heat transfer of nanofluids within waveform microchannel. Comput Model Eng Sci. 2023;134(3):1957-1973 https://doi.org/10.32604/cmes.2022.021481
IEEE Style
M. Moslemi, M. Mahmoodnezhad, S. A. Edalatpanah, S. A. M. Zubair, and H. A. E. Khalifa, “Magnetic Field Effect and Heat Transfer of Nanofluids within Waveform Microchannel,” Comput. Model. Eng. Sci., vol. 134, no. 3, pp. 1957-1973, 2023. https://doi.org/10.32604/cmes.2022.021481


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