TY - EJOU AU - Kumar, Gulshan AU - Alqahtani, Hamed TI - Deep Learning-Based Cancer Detection-Recent Developments, Trend and Challenges T2 - Computer Modeling in Engineering \& Sciences PY - 2022 VL - 130 IS - 3 SN - 1526-1506 AB - Cancer is one of the most critical diseases that has caused several deaths in today’s world. In most cases, doctors and practitioners are only able to diagnose cancer in its later stages. In the later stages, planning cancer treatment and increasing the patient’s survival rate becomes a very challenging task. Therefore, it becomes the need of the hour to detect cancer in the early stages for appropriate treatment and surgery planning. Analysis and interpretation of medical images such as MRI and CT scans help doctors and practitioners diagnose many diseases, including cancer disease. However, manual interpretation of medical images is costly, time-consuming and biased. Nowadays, deep learning, a subset of artificial intelligence, is gaining increasing attention from practitioners in automatically analysing and interpreting medical images without their intervention. Deep learning methods have reported extraordinary results in different fields due to their ability to automatically extract intrinsic features from images without any dependence on manually extracted features. This study provides a comprehensive review of deep learning methods in cancer detection and diagnosis, mainly focusing on breast cancer, brain cancer, skin cancer, and prostate cancer. This study describes various deep learning models and steps for applying deep learning models in detecting cancer. Recent developments in cancer detection based on deep learning methods have been critically analysed and summarised to identify critical challenges in applying them for detecting cancer accurately in the early stages. Based on the identified challenges, we provide a few promising future research directions for fellow researchers in the field. The outcome of this study provides many clues for developing practical and accurate cancer detection systems for its early diagnosis and treatment planning. KW - Autoencoders (AEs); cancer detection; convolutional neural networks (CNNs); deep learning; generative adversarial models (GANs); machine learning DO - 10.32604/cmes.2022.018418