Open Access

ARTICLE

Mechanical Strength and Structural Basis of β₂ Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations

Ning Li^{1, 2, 3}, Xiao Zhang^{1, 2}, Peiwen Li^{1, 2}, Hao Yang^{1, 2}, Chunfang Tong^{1, 2}, Shouqin Lü^{1, 2}, Yan Zhang^{1, 2}, Zhiyi Ye³, Jun Pan^{3, *}, Mian Long^{1, 2, *}

1 Center of Biomechanics and Bioengineering, Key Laboratory of Microgravity (National Microgravity Laboratory), and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, No. 15 Beisihuanxi Road, Beijing, 100190, China.
2 School of Engineering Sciences, University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Shijingshan District, Beijing, 100049, China.
3 Key Laboratory of Biorheological Science and Technology, Chongqing University, Ministry of Education, No.174 Shazhengjie, Shapingba, Chongqing, 400044, China.

*Corresponding Author: Mian Long. E-mail: ; Jun Pan. E-mail: .