Open Access

ARTICLE

Influence of Clip Locations on Intraaneurysmal Flow Dynamics in Patient-specific Anterior Communicating Aneurysm Models with Different Aneurysmal Angle

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1 Key laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education, School of Energy and Power Engineering, Dalian University of Technology. No. 2 Linggong Road, Dalian, 116024, China.
2 School of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
3 The First Affiliated Hospital of University of Science and Technology of China, Hefei, 230036, China.

* Corresponding Author:Lizhong Mu. Email: .

(This article belongs to the Special Issue: Innovations and Current Trends in Computational Cardiovascular Modeling: Molecular, Cellular, Tissue and Organ Biomechanics with Clinical Applications)

Computer Modeling in Engineering & Sciences 2018, 116(2), 175-197. https://doi.org/10.31614/cmes.2018.04191

Abstract

To improve aneurysm treatment, this study examined the influence of clip locations on hemodynamic factors in patient-specific anterior communicating artery (ACoA) aneurysms with different aneurysmal angle. We proposed a simplified classification of ACoA aneurysms using aneurysmal angle, defined by the angle of pivot of the aneurysmal dome and the virtual two-dimensional plane created by both proximal A2 segments of anterior cerebral artery (ACA). ACoA aneurysms with three different aneurysmal angles, which are 15°, 80° and 120°, were analyzed in our study. In this work, we obtained hemodynamics before and after clipping surgery with three clip locations based on clinical clipping strategies in three ACoA aneurysms with different aneurysm angles. Results showed that local high pressure occurs at impingement region of the ACoA aneurysm before clipping and new impingement region close to the clipping location after clipping treatment. For clipping the aneurysm with aneurysmal angle 15° and a wide neck, wall shear stress (WSS) distribution is more uniform when the clipping angle of two clips close to 180° comparing with other two angles. In addition, for clipping the aneurysm with aneurysmal angle 80° and 120°, local high pressure appears on new impingement region and high WSS distributes around the clipping location when the clip plane is normal to the direction of inflow of aneurysm from the dominance of A1 segment of ACA. Hence, we should avoid the impingement of inflow from the A1 segment and choose a favorable clipping location for the fastness of clip. The results of our study could preoperatively give a useful information to the decision of surgical plan.

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