Open Access

ARTICLE

Dimensionless Study on Secretion Clearance of a Pressure Controlled Mechanical Ventilation System with Double Lungs

by Dongkai Shen¹, Qian Zhang¹, Yixuan Wang¹, Huiqing Ge³, Zujin Luo⁴

1 School of Automation Science and Electrical Engineering, Beihang University, Beijing, PR China.
2 The State Key Laboratory of Fluid Power Transmission and Control, Zhejiang University, Hangzhou, China .
3 Department of Respiratory Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang, China.
4 Department of Respiratory and Critical Care Medicine, Beijing Engineering Research Center of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao -Yang Hospital, Capital Medical University, Beijing 100043, China.
+ These two authors should be regarded as Joint First Authors.

*Corresponding author: Yixuan Wang. Email: ; Huiqing Ge. Email: .

Computer Modeling in Engineering & Sciences 2018, 114(2), 117-139. https://doi.org/10.3970/cmes.2018.114.117

Abstract

A pressure controlled mechanical ventilator with an automatic secretion clearance function can improve secretion clearance safely and efficiently. Studies on secretion clearance by pressure controlled systems show that these are suited for clinical applications. However, these studies are based on a single lung electric model and neglect the coupling between the two lungs. The research methods applied are too complex for the analysis of a multi-parameter system. In order to understand the functioning of the human respiratory system, this paper develops a dimensionless mathematical model of double-lung mechanical ventilation system with a secretion clearance function. An experiment is designed to verify the mathematical model through comparison of dimensionless experimental data and dimensionless simulation data. Finally, the coupling between the two lungs is studied, and an orthogonal experiment designed to identify the impact of each parameter on the system.

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Keywords

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