Transperineal prostate biopsy without routine antibiotics demonstrates decreased infection risk
Benjamin J. Lichtbroun1,2,*, Mann Patel2, Alexis Consalvo2, Labeeqa Khizir2, Munisa Said2, Austin Chien2, Kevin Chua1,2, John Pfail1,2, Rachel Passarelli1,2, Vignesh T. Packiam1, David Golombos1, Sammy Elsamra2, Thomas L. Jang1, Arnav Srivastava1,3, Saum Ghodoussipour1
Canadian Journal of Urology, Vol.32, No.1, pp. 55-62, 2025, DOI:10.32604/cju.2025.064701
- 20 March 2025
Abstract Introduction: Infections are the most feared complication of transrectal prostate biopsies, along with growing concerns of antibiotic resistance. Our institution transitioned to a transperineal approach without use of perioperative antibiotics or bowel preparations. We aimed to compare the safety outcomes associated with transperineal and transrectal prostate biopsy techniques. Materials and Methods: A retrospective analysis of patients who underwent transrectal and transperineal prostate biopsies at our institution from 2019–2022 was performed. Results: We identified 319 patients—174 transrectal and 145 transperineal. 8 patients who had transperineal biopsy (5.5%) received peri-operative antibiotics, compared to 100% with transrectal biopsy. 35.86%… More >