John V. Dudinec^1,*, Sabrina M. Wang^1,*, Srinath Kotamarti¹, Kostantinos E. Morris², Thomas J. Polascik¹, Judd W. Moul¹

Canadian Journal of Urology, Vol.30, No.3, pp. 11538-11544, 2023

Abstract Introduction: The clinical utility of concurrent Prostate Health Index (PHI) and ExosomeDx Prostate Intelliscore (EPI) testing is unclear. We sought to examine the performance of combined PHI and EPI testing on men undergoing elevated PSA work up.
Materials and methods: Patients who received both EPI and PHI testing were identified from an institutional database of men referred to urology for an elevated total PSA. Cut points of EPI > 15.6 and PHI ≥ 36 were used to denote a positive test. Patients were placed into one of four groups determined by combination of EPI and PHI results.… More >

Fadl Hamouche, Rei Unno, Nizar Hakam, Leslie Bernal Charondo, Heiko Yang, Justin Ahn, David B. Bayne, Marshall L. Stoller, Thomas Chi

Canadian Journal of Urology, Vol.30, No.3, pp. 11532-11537, 2023

Abstract Introduction: To evaluate the clinical characteristics as well as the postoperative course of urolithiasis patients undergoing a ureteroscopy (URS) without stent placement.
Materials and methods: This was a prospective case cohort study utilizing data collected in the Registry for Stones of the Kidney and Ureter (ReSKU) from a single institution between October 2015 and December 2020. We identified all consecutive patients undergoing URS for stone disease and analyzed data encompassing demographics, medical history, intra and postoperative characteristics, including complications and postoperative symptoms. Univariate and multivariate logistic regression analyses were performed based on the presence or absence of… More >

J. Ryan Mark¹, Leonard G. Gomella¹, Costas D. Lallas¹, Katherine E. Smentkowski¹, Anne Calvaresi¹, Nathan Handley², Robert B. Den³, Patrick Mille², William J. Tester², Jean Hoffman-Censits⁴, Adam P. Dicker³, Edward Klonicke¹, Ethan Halpern⁵, Peter McCue⁵, W. Kevin Kelly², Edouard J. Trabulsi⁶

Canadian Journal of Urology, Vol.30, No.3, pp. 11526-11531, 2023

Abstract Introduction: We report the impact of our 25-year multidisciplinary care delivery model experience on patients with muscle invasive bladder cancer treated at our National Cancer Institute (NCI)-designated Sidney Kimmel Cancer Center at Jefferson University. To our knowledge, our multidisciplinary genitourinary cancer clinic (MDC) is the longest continuously operating center of its kind at an NCI Cancer Center in the United States.
Materials and methods: We selected a recent group of patients with cT2-4 N0-1 M0 bladder cancer seen in the Sidney Kimmel Cancer Center Genitourinary Oncology MDC from January 2016 to September 2019. These patients were identified… More >

Alan W. Partin, Louis R. Kavoussi, Craig A. Peters, Roger R. Dmochowski

Canadian Journal of Urology, Vol.30, No.3, pp. 11525-11525, 2023

Abstract This article has no abstract. More >

Gopal Badlani

Canadian Journal of Urology, Vol.30, No.3, pp. 11522-11524, 2023

Abstract This article has no abstract. More >

Leonard G. Gomella

Canadian Journal of Urology, Vol.30, No.3, pp. 11520-11521, 2023

Abstract This article has no abstract. More >

Bertie Zhang¹, Arinze J. Ochuba², Gregory R. Mullen³, Arun Rai³, Tareq Aro³, David M. Hoenig³, Zeph Okeke³, Jared S. Winoker^1,3

Canadian Journal of Urology, Vol.30, No.4, pp. 11639-11643, 2023

Abstract Percutaneous nephrolithotomy (PCNL) is the gold-standard treatment for large and complex renal stones. Though associated with higher stone-free rates compared to other minimally invasive stone procedures, this comes at the expense of increased morbidity including postoperative pain and discomfort. We describe our enhanced recovery after surgery (ERAS) protocol for PCNL with emphasis on the use of erector spinae plane blocks to improve patient satisfaction and reduce postoperative opioid use and bother. More >

Aly-Khan A. Lalani

Canadian Journal of Urology, Vol.30, No.4, pp. 11633-11638, 2023

Abstract For more than four decades, platinum-based chemotherapy regimens have served as the established standard-of-care for advanced urothelial carcinoma (aUC). However, advancements in our understanding of cancer biology and tumor microenvironment have reshaped the therapeutic landscape and prognosis of this incurable disease. Immune checkpoint inhibitors (ICIs) that target programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are firmly established tools in aUC management, leading to enhanced life span and improved quality of life for patients.
In patients who achieved stable disease or better following platinum-based chemotherapy, maintenance therapy with the PD-L1 antibody… More >

Joaquin Fernandez-Alberti¹, Ramon Coronil², Alejandro Iotti³, Alejandro Nolazco¹, Marcelo Featherston¹

Canadian Journal of Urology, Vol.30, No.4, pp. 11629-11632, 2023

Abstract Calyceal diverticulum (CD) is a rare anatomic anomaly with an incidence of 0.2% to 0.6% in the patients undergoing renal imaging. They are considered benign lesions and malignancy is exceedingly rare. For diagnosis it is suggested to perform a multiphasic contrast-enhanced computed tomography (CT) evidencing a diverticulum of the pelvicalyceal system with thin-walled cavities communicating with the central collecting system. However, they can be usually mistaken as kidney cancers leading to unjustified nephrectomy. Here, we present a case of a 34-year-old patient who underwent surgery in 2022 due to suspected kidney cancer and histopathological analysis More >

Jordan Sarver, Remington Farley, Shane Daugherty, Jordan Bilbrew, Joshua Palka

Canadian Journal of Urology, Vol.30, No.4, pp. 11624-11628, 2023

Abstract Introduction: Difficult and traumatic urethral catheterization is a common reason for urologic consult. Catheter insertion and management is common for patients who are managed in the hospital setting.
Materials and methods: A four-question survey was distributed across three hospitals at a single-institution.
Results: A total of 41 nursing staff responses were recorded. Forty-four percent of the nursing staff reported prior participation in a traumatic catheter insertion. Ninety percent of total responders reported a prior involvement with a difficulty catheter.
Conclusion: Patient morbidity and healthcare costs regarding traumatic and difficult catheterization is significant. Utility of protocols and education could potentially More >