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  • Open Access

    ARTICLE

    An Optimized Neural Network with Bat Algorithm for DNA Sequence Classification

    Muhammad Zubair Rehman1, Muhammad Aamir2,*, Nazri Mohd. Nawi3, Abdullah Khan4, Saima Anwar Lashari5, Siyab Khan4

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 493-511, 2022, DOI:10.32604/cmc.2022.021787

    Abstract

    Recently, many researchers have used nature inspired metaheuristic algorithms due to their ability to perform optimally on complex problems. To solve problems in a simple way, in the recent era bat algorithm has become famous due to its high tendency towards convergence to the global optimum most of the time. But, still the standard bat with random walk has a problem of getting stuck in local minima. In order to solve this problem, this research proposed bat algorithm with levy flight random walk. Then, the proposed Bat with Levy flight algorithm is further hybridized with three different variants of ANN.… More >

  • Open Access

    ARTICLE

    Construction of an Energy-Efficient Detour Non-Split Dominating Set in WSN

    G. Sheeba1,*, T. M. Selvarajan2

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 689-700, 2022, DOI:10.32604/cmc.2022.021781

    Abstract Wireless sensor networks (WSNs) are one of the most important improvements due to their remarkable capacities and their continuous growth in various applications. However, the lifetime of WSNs is very confined because of the delimited energy limit of their sensor nodes. This is the reason why energy conservation is considered the main exploration worry for WSNs. For this energy-efficient routing is required to save energy and to subsequently drag out the lifetime of WSNs. In this report we use the Ant Colony Optimization (ACO) method and are evaluated using the Genetic Algorithm (GA), based on the Detour non-split dominant set… More >

  • Open Access

    ARTICLE

    FPGA Implementation of 5G NR Primary and Secondary Synchronization

    Aytha Ramesh Kumar1,*, K. Lal Kishore2

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 1585-1600, 2022, DOI:10.32604/cmc.2022.021573

    Abstract The 5G communication systems are widely established for high-speed data processing to meet users demands. The 5G New Radio (NR) communications comprise a network of ultra-low latency, high processing speeds, high throughput and rapid synchronization with a time frame of 10 ms. Synchronization between User Equipment (UE) and 5G base station known as gNB is a fundamental procedure in a cellular system and it is performed by a synchronization signal. In 5G NR system, Primary Synchronization Signal (PSS) and Secondary Synchronization Signal (SSS) are used to detect the best serving base station with the help of a cell search procedure.… More >

  • Open Access

    ARTICLE

    MagneFi: Multiuser, Multi-Building and Multi-Floor Geomagnetic Field Dataset for Indoor Positioning

    Imran Ashraf1, Muhammad Usman Ali2, Soojung Hur1, Gunzung Kim1, Yongwan Park1,*

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 1747-1768, 2022, DOI:10.32604/cmc.2022.020610

    Abstract Indoor positioning and localization have emerged as a potential research area during the last few years owing to the wide proliferation of smartphones and the inception of location-attached services for the consumer industry. Due to the importance of precise location information, several positioning technologies are adopted such as Wi-Fi, ultrawideband, infrared, radio frequency identification, Bluetooth beacons, pedestrian dead reckoning, and magnetic field, etc. Although Wi-Fi and magnetic field-based positioning are more attractive concerning the deployment of Wi-Fi access points and ubiquity of magnetic field data, the latter is preferred as it does not require any additional infrastructure as other approaches… More >

  • Open Access

    ARTICLE

    The expression and function of miR-376a-3p/DLX axis in gastric cancer cells

    YAN ZHANG, CHAOJUN ZHANG*, ZHEN CAO, ZHANWEI ZHAO, LIN CHEN*

    BIOCELL, Vol.46, No.9, pp. 2073-2080, 2022, DOI:10.32604/biocell.2022.020635

    Abstract Gastric cancer (GC) was referred to a malignant tumor of the digestive tract originating from the epithelium of gastric mucosa. Transcription factor DLX5 was verified as an oncogene in various types of tumors, while miR-376a-3p was speculated as a tumor suppressor. Based on the bioinformatics database, we hypothesized that miR-376a participated in the regulation of GC development by targeting DLX5. Compared with adjacent tissue, a significant increase of DLX5 expression was determined in GC tissues, but the expression level is significantly reduced in miR-376a. Similar expression signature of DLX5 and miR-376a was also determined between 4 GC cells (HGC, SGC,… More >

  • Open Access

    ARTICLE

    Transcriptome analysis combined with metabolome analysis reveals the significant functions of CesA genes in cotton (Gossypium hirsutum) fiber length development

    ZHENKUI CUI1,#,*, GUIQIN SUN2,#,*, QUANZHI ZHAO1

    BIOCELL, Vol.46, No.9, pp. 2133-2144, 2022, DOI:10.32604/biocell.2022.020512

    Abstract Cotton is widely distributed worldwide, and improving the quality of its fiber is one of the most important tasks in cotton breeding. Cotton fibers are primarily composed of cellulose, which is synthesized by CesA complexes (CSCs). However, the functions of CesA genes in cotton fiber development have not been comprehensively analysed. In this study, the cotton transcriptome and metabolome were used to investigate the function of CesA genes in fiber development. Finally, 321 metabolites were obtained, 84 of which were associated with the corresponding genes. Interestingly, a target gene named Gh_A08G144300, one of the CesA gene family members, was closely… More >

  • Open Access

    ARTICLE

    Identification of a new Hazelnut disease in Liaoning Province: Hazelnut husk brown rot

    JUN SUN1,*, MING XIE1, JIACHEN HAO1, NAN MAO1, LIJING CHEN2,*, YUANYUAN QIN3

    BIOCELL, Vol.46, No.9, pp. 2145-2149, 2022, DOI:10.32604/biocell.2022.020500

    Abstract Hazelnut husk brown rot has been identified as a new disease in Liaoning Province in recent years. The objective of this study as to identify the pathogen. [Method] In this study, a standard sample of hazelnut husk brown rot was collected from Songmudao Base in Dalian City, Liaoning Province. The pathogen was identified by the studies of the morphology, pathogenicity, and analyses of ITS and LSU sequences. The pathogen was isolated and purified, which was confirmed by Koch’s postulates. The symptoms after inoculation were the same as those collected directly from a diseased tree, which showed that it was the… More >

  • Open Access

    REVIEW

    Efficacy of oral consumption of curcumin/ for symptom improvement in inflammatory bowel disease: A systematic review of animal models and a meta-analysis of randomized clinical trials

    MARLA DE CERQUEIRA ALVES1, MONISE OLIVEIRA SANTOS1, NASSIB BEZERRA BUENO1, ORLANDO ROBERTO PIMENTEL DE ARAÚJO2, MARÍLIA OLIVEIRA FONSECA GOULART2,3,4, FABIANA ANDRÉA MOURA1,5,*

    BIOCELL, Vol.46, No.9, pp. 2015-2047, 2022, DOI:10.32604/biocell.2022.020407

    Abstract

    The roots of the vegetal Curcuma due to its high content of polyphenols, has been used successfully in several clinical situations. This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease (IBD). A systematic review of animal models and randomized clinical trials (RCTs) was conducted by searching the following electronic databases: PubMed, CENTRAL, LILACS, Science Direct, and ClinicalTrials.gov. From 997 found records, 62 were included. More than 90% of the animal studies reported an improvement in macroscopic, histologic and/or functional activity; 80% identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.… More >

  • Open Access

    ARTICLE

    Effects of two vectors on the expression of the NbNAC1 transcription factor and preparation of its polyclonal antibody

    FENG ZHU*, QINQIN ZHANG, YANGKAI ZHOU, QIPING ZHANG, MENGYAO CAO, ZHAOLIN JI

    BIOCELL, Vol.46, No.9, pp. 2123-2131, 2022, DOI:10.32604/biocell.2022.020229

    Abstract The NAC (NAM, ATAF, and CUC) superfamily is one of the largest plant-specific families containing transcription factors. An increasing number of studies suggest that NAC1 is involved in plants response to different biotic and abiotic stimulis. Nicotiana benthamiana is a widely used system for evaluating plant-pathogen interactions. In order to study the biochemical function of NbNAC1, NbNAC1 protein and antibody are essential. Therefore, we focused on developing a prokaryotic expression system for producing the Nicotiana benthamiana NbNAC1 protein of in Escherichia coli and the preparation of its polyclonal antibody. Firstly, we constructed two different molecular weight prokaryotic expression vectors: pGE… More >

  • Open Access

    ARTICLE

    Wnt3a-induced ST2 decellularized matrix ornamented PCL scaffold for bone tissue engineering

    XIAOFANG WANG1, XIAOLIN TU1,2,*, YUFEI MA1, JIE CHEN1, YANG SONG3, GUANGLIANG LIU1

    BIOCELL, Vol.46, No.9, pp. 2089-2099, 2022, DOI:10.32604/biocell.2022.020069

    Abstract The limited bioactivity of scaffold materials is an important factor that restricts the development of bone tissue engineering. Wnt3a activates the classic Wnt/β-catenin signaling pathway which effects bone growth and development by the accumulation of β-catenin in the nucleus. In this study, we fabricated 3D printed PCL scaffold with Wnt3a-induced murine bone marrow-derived stromal cell line ST2 decellularized matrix (Wnt3a-ST2-dCM-PCL) and ST2 decellularized matrix (ST2-dCM-PCL) by freeze-thaw cycle and DNase decellularization treatment which efficiently decellularized >90% DNA while preserved most protein. Compared to ST2-dCM-PCL, Wnt3a-ST2-dCM-PCL significantly enhanced newly-seeded ST2 proliferation, osteogenic differentiation and upregulated osteogenic marker genes alkaline phosphatase (Alp),… More >

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